摘要
目的:对比分析超声刀与电刀在乳腺癌改良根治术中的安全性及优缺点。方法:计算机全面检索MEDLINE、EMBASE、Cochrane library、万方、CNKI、CBM数据库,查找比较超声刀和电刀在乳腺癌改良根治术中应用的前瞻性对照试验。对入选文献进行质量评价后,从符合要求的文献中提取数据资料,采用Rev Man5软件进行Meta分析。结果:纳入11项合格研究,共817例乳腺癌患者。其中超声刀手术组404例,传统电刀手术组413例。Meta结果显示:与电刀手术组相比,超声刀组术中出血量明显减少、淋巴结检出数目多。在手术时间、术后引流量、引流天数和皮下积液发生方面略优于电刀组。结论:在乳腺癌改良根治术中超声刀对比电刀组,术中出血少,淋巴结检出数目多,安全可行。受限于纳入文章的质量和研究数量,上述结论尚需进一步多中心、大样本、高质量的前瞻性研究加以证实。
Objective：To compare the safety between harmonic scalpel and electrocautery in modified radical mas- tectomy using meta - analysis. Methods ： MEDLINE, EMBASE, Cochrane library, Wanfang, CNKI, CBM were searched for the prospective controlled trials of ultrasonic dissection versus electrocautery for mastectomy. Then, assess the qual- ities of the included trials and perform a meta - analysis with Revman5 software. Results： Eleven trials were included in the analysis with 817 masteetomies, involving 404 cases in harmonic scalpel group and 413 cases in controls. Meta - analysis showed that, compared with electroeautery group, the harmonic scalpel group showed more less intra - oper- ative blood loss, more number of lymph nodes detected, operative time, total postoperative drainage, drainage days and seroma development were slightly superior to control group. Conclusion：Ultrasonic dissection in modified radical mas- tectomy was as safe as that of the eleetrocautery with the advantage of less intra - operative blood loss and more num- ber of lymph nodes detected. But limited by the quantity and quality of studies included, larger sample, high quality RCTs are needed to verify the conclusion.
出处
《现代肿瘤医学》
CAS
2015年第21期3110-3114,共5页
Journal of Modern Oncology
基金
湖北省科技计划自然科学基金(编号:2011CH13020)
关键词
超声刀
电刀
乳腺癌改良根治术
META分析
harmonic scalpel, electrocautery, modified radical mastectomy, Meta analysis
