摘要
目的:分析抗焦虑抑郁对室性心律失常患者的临床疗效及意义。方法:选择室性心律失常合并焦虑抑郁状态的患者132例随机分为治疗组65例和对照组67例,对照组行常规治疗,治疗组在常规治疗基础上加服抗抑郁焦虑药物治疗,6周后观察治疗前后两组汉密尔顿焦虑抑郁量表评分、早搏数量以及心率变异性变化。结果:治疗组控制率、控制+显效率高于对照组,无效率低于对照组;比较治疗前后,治疗组心率变异性时域指标PNN50(相邻NN间期差值超过50ms的心搏数所占百分比)、RMSSD(相邻NN间期差值的均方根),以及频域指标LF/HF(低频功率与高频功率的比值)高于治疗前、同期对照组;治疗组HAMD、HAMA水平低于治疗前、同期对照组,差异具有统计学意义(<0.05)。结论:对室性心律失常患者伴发的焦虑抑郁症状进行抗抑郁抗焦虑治疗,有助于增进抗心律失常药物疗效,提高心率变异性,改善自主神经功能紊乱,减轻抑郁与焦虑症状,提高其生活质量。
Objective： To analyze anxiety and depression symptoms treatment and significance under ventricular premature beats patients.Methods：To select 66 patients given by antiarrhythmic drugs and antidepressant placebo drugs as control group,and 66 patients given by antiarrhythmic drugs,antidepressant treatment and comprehensive intervention as observation group,after 6 weeks,compare their clinical effect and relative indexes.Result： Before treatment,control rate,control and effective rate in observation group were higher than ones in control group,after treatment,PNN50 in observation group was higher than before treatment and control group in the same time,r MMSD,LF/HF,SDS,SAS in observation group were lower than before treatment,control group in the same time,difference had statistical significance（P〈0.05）.Conclusion：Given by comprehensive treatment for anxiety and depression symptoms under ventricular premature beats patients,it can be able to promote antiarrhythmic drug effect,and reduce depression and anxiety symptoms.
出处
《农垦医学》
2015年第1期9-12,共4页
Journal of Nongken Medicine
关键词
心脏早搏
焦虑
抑郁
Ventricular premature beats
Anxiety
Depression
