摘要
目的:探讨急性中毒急诊内科相关影响因素,并总结应对措施,以期提高临床治疗水平。方法:回顾性分析2010至2014年200例急性中毒患者,对其中的急诊内科影响因素进行总结。结果:急性中毒预后急诊内科相关影响因素有接触毒物时间长(≥60 min)、农药中毒、消化道中毒、PSS评分(≥3分)、p H值(<7.3)、碳酸血症(Pa CO2≥100 mm Hg)、APACHEⅡ评分(≥10分)、SOFA评分(≥5分)、肌酸激酶同工酶(≥30 U/L)、服毒剂量大(≥100 m L)、胆碱酯酶(≥350U/L)、血液净化时间长(≥2 h)、初次用药时间长(≥10 min)(P均<0.05),而和性别、年龄无关(P>0.05);采用Logostic多因素分析,其中农药中毒、PSS评分、p H值、碳酸血症、APACHEⅡ评分、SOFA评分、肌酸激酶同工酶、服毒剂量、胆碱酯酶、血液净化时间、初次用药时间是急性中毒预后急诊内科独立危险因素(P均<0.05)。结论:急性中毒患者急诊内科相关影响因素和农药中毒、PSS评分、p H值、碳酸血症、APACHEⅡ评分、SOFA评分、肌酸激酶同工酶、服毒剂量、胆碱酯酶、血液净化时间、初次用药时间等均有关,在临床上要早期针对性治疗。
Objective： To explore the emergency medical factors affecting the prognosis of patients with acute poisoning and summarize countermeasures,in order to improve the level of clinical treatment. Methods： From 2010 to 2014 200 cases of patients with acute poisoning were retrospectively analyzed to summarize the emergency medical factors affecting the prognosis of patients with acute poisoning. Results： The emergency medical factors affecting the prognosis of patients with acute poisoning were long contact poison（ ≥60 min）,pesticide poisoning,digestive tract toxicity,PSS score（ ≥3）,p H（ 〈7. 3）,carbonic acid hematic disease（ Pa CO2≥100mm Hg）,APACHE Ⅱ score（ ≥10）,SOFA score（ ≥5）,creatine kinase isoenzyme（ ≥30 U / L）,drug doses（ ≥100 m L）,cholinesterase（ ≥350 U / L）,long time blood purification（ ≥2 h）,the first long time duration（ ≥10 min））（ P〈0. 05）,and had nothing to do with gender,age（ P〉0. 05）. The independent risk factors affecting the prognosis of patients with acute poisoning were pesticide poisoning,PSS score,p H value,carbonic acid hematic disease,APACHE Ⅱ score,SOFA score,creatine kinase isoenzyme,drug dosage,cholinesterase,blood purification time,first time duration（ P〈0. 05） by using logostic multi-factor analysis. Conclusion： The emergency medical factors affecting the prognosis of patients with acute poisoning were pesticide poisoning,PSS score,p H value,carbonic acid hematic disease,APACHE Ⅱ score,SOFA score,creatine kinase isoenzyme,drug dosage,cholinesterase,blood purification time,first time duration and it must be early targeted treatment.
出处
《川北医学院学报》
CAS
2015年第5期655-658,共4页
Journal of North Sichuan Medical College
关键词
急性中毒
急诊内科
影响因素
预防措施
Acute poisoning
Emergency medicine
Influencing factor
Prevention measures
