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综合疗法治疗慢性阻塞性肺疾病急性加重期并呼吸衰竭疗效及安全性评价 被引量:12

The Efficacy and Safety Evaluation of Comprehensive Treatment of Chronic Obstructive Pulmonary Disease With Respiratory Failure
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摘要 目的分析纤维支气管镜肺泡灌洗联合无创正压通气综合治疗慢性阻塞性肺疾病急性加重期并呼吸衰竭疗效及安全性。方法随机选98例我院收治的慢性阻塞性肺疾病急性加重期并呼吸衰竭患者,随机平均分成两组,对照组实施常规治疗辅助无创正压通气法,实验组实施纤维支气管镜肺泡灌洗联合无创正压通气综合治疗,1个疗程15 d后对比分析相关指标。结果对照组治疗总有效率为63.3%;实验组治疗总有效率优于对照组(P<0.05);对比两组患者的血气分析指标,试验组的血气分析指标变化幅度均优于对照组,如Pa CO2、Pa O2、Sa O2、p H等,差异有统计学意义(P<0.05)。结论纤维支气管镜肺泡灌洗联合无创正压通气综合疗法治疗慢性阻塞性肺疾病急性加重期并呼吸衰竭疗效良好,安全性高。 Objective To analyze the bronchoscopy lavage combined with noninvasive positive pressure ventilation in the comprehensive treatment of chronic obstructive pulmonary disease and respiratory failure. Methods 98 cases were randomly selected in our hospital of chronic obstructive pulmonary disease with acute exacerbation and respiratory failure patients. They were divided into two groups,the control group used conventional therapy assisted noninvasive positive pressure ventilation method,and the experimental group used bronchoscopy lavage joint NIPPV for comprehensive treatment.After a course of 15 d,comparative to analyze relevant indicators. Results The total effective rate in the control group was 63.3%,the total efficiency of the experimental group was better than the control group(P〈0.05). Blood gas analysis showed that two groups of patients,the Blood gas analysis indicators changed in experimental group was significantly better than the control group,such as Pa CO2, Pa O2, Sa O2,p H,the difference was significant,P〈0.05. Conclusion Bronchoscopy lavage combined with noninvasive positive pressure ventilation in therapy of chronic obstructive pulmonary disease and respiratory failure have a significant effect,and were safety.
作者 张小波
出处 《中国卫生标准管理》 2015年第27期77-79,共3页 China Health Standard Management
关键词 综合疗法 中西医结合 慢性阻塞性肺疾病 急性加重期 呼吸衰竭 Combination therapy Integrative Medicine Chronic obstructive pulmonary disease Acute exacerbation Respiratory failure
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