摘要
目的探讨肾小球滤过率测定对早期糖尿病肾病患者治疗的作用。方法选取2012年1月~2014年1月我院收治的早期糖尿病肾病患者以及在此期间来我院进行体检的正常人为研究对象。分为早期糖尿病组与正常组,每组各30例;同时对两组进行肾小球滤过率测定,比较两组的肾小球滤过率。结果正常白蛋白尿组、微量白蛋白尿组的GFR高于正常组平均指标,且两者与正常组相比差异有统计学意义（P〈0.05）;大量白蛋白尿组的GFR指标低于正常组,两者相比差异有统计学意义（P〈0.05）;随UAER的增多,糖尿病患者的BUN、Cr升高,且只有大量白蛋白尿组患者的BUN、Cr与正常组相比差异有统计学意义（P〈0.05）。结论利用肾小球滤过率测定对早期糖尿病患者进行检查,其结果可以准确反映早期糖尿病肾病患者的肾损害状况,从而为临床治疗提供参考,因此值得临床推广应用。
Objective To investigate the effect of the determination of glomerular filtration rate in treatment of early diabetic nephropathy. Methods Patients with early diabetic nephropathy and normal in our hospital from January 2012 to January 2014 were selected as a medical study,and divided into an early diabetes group and a normal group,30 cases in each group.The glomerular filtration rate between the two groups were determined and compared. Results GFR average index in normal albuminuria group and microalbuminuria group was higher than that in normal group, and difference in the two group compared with the normal group was significant（P〈0.05）;A large number of albuminuria GFR index was lower than that in the normal group,with significant difference（P〈0.05）;With UAER,diabetic patients with elevated BUN,Cr,and only a large number of albuminuria group of patients with BUN,Cr significant difference compared with the normal group（P〈0.05）. Conclusion Using the determination of glomerular filtration rate for early check in diabetic patients,the result can accurately reflect the status of early diabetic nephropathy in patients with renal damage,so as to provide reference for clinical treatment,is worthy of clinical application.
出处
《中国医药科学》
2015年第18期158-159,177,共3页
China Medicine And Pharmacy
关键词
早期糖尿病肾病患者
肾小球滤过测定
作用分析
Patients with early diabetic nephropathy
Glomerular filtration rate test
Effect analysis
