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不同浓度氟化物对氟斑牙牙釉质的影响

Effects of different concentrations of fluoride on tooth enamel fluorosis
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摘要 目的探讨不同浓度氟化物对氟斑牙牙釉质的硬度值及表面微观结构的影响。方法 2012年6月~2014年6月期间收集氟斑恒牙60颗,按照随机数字表法分为对照组、低氟组及高氟组。对照组置于蒸馏水中,低氟组置于低浓度氟化液中,高氟组置于高浓度氟化液中。用显微硬度计和扫描电镜分别测定3组浸泡前后的釉质表面硬度值和釉质表面微观及形态的变化。结果浸泡后,低氟组牙釉质显微硬度最高,高于对照组和高氟组(P〈0.01),而对照组牙釉质显微硬度高于高氟组(P〈0.01)。对照组浸泡后牙釉质显微硬度和浸泡前比较无明显变化(P〉0.05),低氟组浸泡后牙釉质显微硬度明显较浸泡前提高(P〈0.01),高氟组浸泡后牙釉质显微硬度明显较浸泡前降低(P〈0.01)。扫描电镜照片显示,对照组样本与高氟组样本釉质表面未见反应物沉积,低氟组样本釉质表面可见反应物沉积。结论低浓度氟化物制剂可防止牙釉质脱矿、促进牙釉质再矿化、提升氟斑牙患者牙釉质硬度,进而保持患者牙齿健康。 Objective To study the effect of different concentrations of fluoride on dental enamel hardness values and surface microstructure. Methods 60 fluorosis teeth were collected between June 2012 to June 2014, andaccording to the random number table method they were divided into the control group, low fluoride group and high fluoride group. The control group were placed in distilled water, low fluoride group were placed in the low concentration fluoride solution, high fluoride group were placed in the high concentration fluoride solution. Microhardness and scan electron micrography were used respectively to determinate the changes in enamel surface hardness and enamel surface micro morphology of three groups before and after immersion. Results After soaking, the enamel microhardness of low fluoride group was highest, higher than that of control group and high fluoride group(P〈0.01), and enamel microhardness of control group was higher than that of group high fluoride(P〈0.01). The enamel microhardness of control group before and after soaking was of no significant difference(P〉0.05), and the enamel microhardness of low fluoride group after soaking was significantly increased than before soaking(P〈0.01), and in group high fluoride after soaking the enamel microhardness was significantly reduced than before soaking(P〈0.01). Scan electron micrography picture showed, in control group and high fluoride group enamel surface had no reaction deposits, enamel surface of low fluoride group had reaction deposits. Conclusion Low concentration of fluoride preparation can prevent the enamel demineralization and promote enamel mineralization again, fluorine spot tooth enamel hardness patients, which can keep the patient dental health.
作者 陶波 宁颖圆
出处 《中国医药科学》 2015年第18期22-25,共4页 China Medicine And Pharmacy
关键词 氟斑牙 牙釉质 显微硬度 Dental fluorosis Enamel Fluoride Microhardness
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参考文献19

  • 1Rango T, Vengosh A, Jeuland M, et al.Fluoride exposure from groundwater as reflected by urinary fluoride and children's dental fluorosis in the Main Ethiopian Rift Valley[J].Sci Total Environ,2014,496 ( 7 ) : 188-197. 被引量:1
  • 2Zhang Y, Kim JY, Horst O, et al.Fluorosed Mouse Ameloblasts Have Increased SATB1 Retention and Got q Aetivity[J].PLoS One,2014,9 ( 8 ): e103994. 被引量:1
  • 3Chou R, Cantor A, Zakher B, et al.Preventing dental caries in children &h; 5 years: systematic review updating USPSTF recommendation[J].Pediatrics, 2013,132 ( 2 ): 332-350. 被引量:1
  • 4Clark MB, Slayton RL, Section on oral health, et al. Fluoride use in caries prevention in the primary care setting[J].Pediatrics,2014,134 ( 3 ) : 626-633. 被引量:1
  • 5Atia GS, May J.Dental fluorosis in the paediatric patient[J]. Dent Update,2013,40 (10): 836-839. 被引量:1
  • 6Castro KS, Ferreira AC, Duarte RM, et al.AcceI~tability, efficacy and safety of two treatment protocols for dental fluorosis : a randomized clinical trial[J].J Dent, 2014,42 ( 8 ) : 938-944. 被引量:1
  • 7Popov I, Carrato A, Sobrero A, et al.Raltitrexed (Tomudex) versus standard leucovorin-modulated bolus 5-fluorouracil: Results from the randomised phase III Pan-European Trial in Adjuvant Colon Cancer 01 (PETACC-1) [J].Eur J Cancer,2008,44 ( 15 ): 2204-2211. 被引量:1
  • 8Jackman AL, Farrugia DC, Gibson W, Kimbell R, Harrap KR, Stephens TC, et al.ZD1694 (Tomudex): a new thymidylate syn-thase inhibitor with activity in colorectal cancer[J].Eur J Cancer, 1995,31A ( 7-8): 1277-1282. 被引量:1
  • 9Gravalos C, Salut A, Garc I a-Gir 6 n C, et al. A randomized phase II study to compare oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4) versusoxaliplatin plus raltitrexed (TOMOX) as first- line chemotherapy for advanced colorectal cancer[J].Clin Transl Oncol,20i2, 14 ( 8 ) : 606-612. 被引量:1
  • 10Bami S, Ghidini A, Coinu A, et al.A systematic review of raltitrexed-based first-line chemotherapy in advanced colorectal cancer[J].Anticancer Drugs, 2014,25 ( 10 ): 1122-1128. 被引量:1

二级参考文献53

  • 1孙殿军,刘立志.我国饮茶型氟中毒研究的回顾及展望[J].中国地方病学杂志,2005,24(1):1-2. 被引量:67
  • 2刘运起,孙殿军,杨晓静,孙玉富,刘立志,李德云,周定友,张莉莉,吴玉.儿童饮砖茶水摄氟量与氟斑牙剂量效应关系及其上限值[J].中国地方病学杂志,2005,24(6):645-648. 被引量:11
  • 3陈志刚,张婕,陈玉红.茶氟概论[J].安徽农业科学,2006,34(4):688-689. 被引量:5
  • 4王金明,刘海涛,马俊杰,王俊东.氟中毒及其相关研究技术[J].动物医学进展,2006,27(3):51-54. 被引量:13
  • 5万晓曼,陈斌.865名大学生口腔健康状况的调查[J].右江民族医学院学报,2006,28(5):897-898. 被引量:1
  • 6Jemal A, Bray F, Center MM, et al. Global cancer statistics [J] . CA: A Cancer Journal for Clinicians, 20 11 ,61 (2) : 69 - 90. 被引量:1
  • 7Parkin DM, Pisani P, Ferlay J. Global cancer statistics [J] . CA: A Cancer Journal for Clinicians,1999,49(1) :33 -64. 被引量:1
  • 8Sena K, Morotome Y , Baba 0, et al. Gene expression of growth differentiation factors in the developing periodontium of rat molars [J] . Journal of Dental Research, 2003 ,82 (3 ) : 166 - 17l. 被引量:1
  • 9Thuss-Patience PC, Kretzschmar A, Bichev D, et al. Survival advantage for irinotecan versus best supportive care as second-line chemotherapy in gastric cancer - a randomized phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO) [J] . European Journal of Cancer, 2011 ,47 (15) : 2306 - 2314. 被引量:1
  • 10Kim SH, Lee GW , Go SI, et al. A phase II study of irinotecan, continuous 5-fluorouracil, and leucovorin (FOLFIRI) combination chemotherapy for patients with recurrent or metastatic gastric cancer previously treated with a fluoropyrimidine-based regimen [J] . American Journal of Clinical Oncology ,2010 ,33 (6) :572 - 576. 被引量:1

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