摘要
分析老年慢性阻塞性肺疾病(COPD)急性加重期(AECOPD)住院患者的痰菌构成及耐药特点,为临床合理选择抗菌药物提供依据。采集2012年1月1日~2012年12月31日入住我院的426例老年(≥60岁)AECOPD患者的痰液行一般菌、真菌培养及药敏试验,分析老年AECOPD患者痰的病原菌构成及耐药特点。结果显示老年AECOPD患者痰培养以革兰阴性杆菌为主,其次为真菌,革兰阳性球菌较少。居前三位的革兰阴性杆菌依次为鲍曼不动杆菌、肺炎克雷伯菌和铜绿假单胞菌,且耐药率较高,尤其鲍曼不动杆菌对多种抗菌药物的耐药率达50%以上。
To analyze the pathogens distribution and antimicrobial resistance in sputum specimens m elderly mpat^ents wlm AECOPD in our hospital, hope to provide valuable clinical reference for the selection of antibiotic agents. We collected the sputum of 426 elder inpatients （≥60 years old） with AECOPD in our hospital during Jan. 2012 to Dee. 2012. The bacteria and fungi were isolated and we do the experiment of patl^ogen susceptibility. Gram negative bacterium play a major role, fungus in the second; Gram positive bacterium rare. Top three Gram negative bacterium in sputum culture were as follows： Acinetobacter baumannii, Klebsiella pneumoniae~ Pseudomonas aeruginosa, and showed high resistance to many antimicrobiat agents. Acinetobacter baumannii are 50% resistant to many antimicrobial agents.
出处
《医学与哲学（B）》
2015年第9期51-55,共5页
Medicine & Philosophy(B)
关键词
慢性阻塞性肺疾病
急性加重期
病原菌
耐药性
基础疾病
chronic obstructive pulmonary disease, acute exacerbation period, pathogens, antimicrobial resistance, basic disease
