摘要
目的 探讨高压氧（hyperbaric oxygen,HBO）预处理能否降低胫腓骨远端开放性骨折患者术后并发症的发生率.方法 复旦大学附属中山医院2004年1月至2013年3月胫腓骨远端开放性骨折患者287例,经患者知情同意,签署知情同意书及医院伦理委员会批准,分为HBO预处理组149例和对照组138例,在内固定手术前常规治疗方案基础上,预处理组应用HBO治疗,对照组未实施HBO治疗,随访12 ～26个月,比较2组术后并发症发生率、功能健康水平情况.结果 预处理组术后并发症的发生率（18.8％）明显低于对照组（38.4％）,差异有统计学意义（P＜0.05）;预处理组术后功能健康水平方面优于对照组,2组差异有统计学意义（P＜0.05）.结论 术前对胫腓骨远端开放性骨折患者进行HBO预处理,能有效降低术后并发症发生率,提高术后功能健康水平.
Objective To investigate whether hyperbaric oxygen preconditioning （HBOP） could decrease the incidence of postoperative complications in patients with distal tibiofibular fracture.Methods Two hundred and eighty-seven cases of distal tibiofibular open fracture admitted into the Zhongshan Hospital Affiliated to Fudan University for treatment from January 2004 to March 2013 were randomly divided into 2 groups：the hyperbaric oxygen preconditioning （HBOP） group（n =149）and the control group（n =138）.On the basis of routine therapy prior to internal fixation,the HBOP group was administered with HBO therapy,while the control group was left there without HBO therapy.All the patents had 12-26 months of medical follow-ups to assess the results of different treatment.Then,the incidence of postoperative complications and functional recovery level were compared between the 2 groups.Results The incidence of postoperative complications in the HBOP group was obviously lower than that in the control group （P 〈 0.05）.And functional recovery level in the patients of the HBOP group was significantly superior to that of the control group,and statistical significance could be noted,when comparisons were made between the 2 groups （P 〈 O.05）.Conclusions HBO preconditioning before surgical treatment of the patients with distal tibiofibular fracture could effectively decrease the incidence of postoperative complications and improve their functional recovery level.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2015年第4期293-296,共4页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
高压氧
预处理
胫腓骨远端开放性骨折
并发症
Hyperbaric oxygen
Preconditioning
Distal tibiofibular open fracture
Complications
