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熔体静电纺丝技术及其在生物医学中的应用 被引量:6

Application of melt electrospinning process in biomedicine field
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摘要 熔体静电纺丝技术不使用溶剂,可制备连续的超细纤维,在生物医学领域有着广泛的应用。从流体黏度、射流特点、纤维直径、纺丝效果方面比较了熔体静电纺丝与溶液静电纺丝的差异;介绍了近年来熔体静电纺丝的技术进展,如激光加热熔体静电纺丝技术、同轴熔体静电纺丝技术,以及熔体静电纺丝直写技术等;综述了熔体静电纺丝技术在组织工程、伤口敷料和药物释放方面的应用;指出熔体静电纺丝应进一步优化加工工艺,获得具有适度自粘结结构的支架,从而提高其应用性。 Melt eleetrospinning process was used for producing continuous microfibers in absence of solvents and was widely ap- plied in biomedicine field. The difference in melt eleetrospinning process and solution eleetrospinning process was compared from the aspects of fluid viscosity, jet characteristics, fiber diameter and spinning result. The technology development of melt electro- spinning process was described in the latest years, such as laser heating melt electrospinning, coaxial melt electrospinning, melt electrospinning in a direct writing mode. The application of melt electrospinning process was emphatically reviewed in the fields of tissue engineering, wound dressing and drug releasing. It was pointed out that the melt electrospinning process should be further optimized in order to obtain the rational self-bonded structure of brackets, thereby enhancing its applicability.
出处 《合成纤维工业》 CAS 2015年第5期39-42,共4页 China Synthetic Fiber Industry
基金 北京自然科学基金项目(2141002)
关键词 熔体静电纺丝 超细纤维 生物医学 组织工程 伤口敷料 药物释放 melt electrospinning microfiber biomedicine tissue engineering wound dressing drug release
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