摘要
Background：High intracuffpressure can cause severe pharyngeal complications including sore throat or hoarseness after laryngeal mask airway （LMA） removal postoperatively.Though the application of minimum effective cuffinflating volume is suggested to maintain airway sealing and adequacy of ventilation for patients receiving general anesthesia with LMA at lower level of the intracuffpressure,it is currently not a standard care in most of the anesthetic departments.In this study,the minimum effective cuff inflating volume was determined for classic LMA Well LeadTM （Well Lead Medical Co.,Ltd.,China） and its impact on postoperative pharyngeal complications was also explored.Methods：Patients with American Society of Anesthesiologists physical status （Ⅰ-Ⅲ） undergoing the short-duration urological surgery were recruited in this trial.First,the minimum effective cuff inflating volume was determined for size 4 or 5 LMA Well LeadTM in the study 1.Immediately following placement and confirmation of ideal LMA position,the cuff was inflated with 5,7,10 ml of air and up to 30 ml at 5 ml increment.The intracuff pressure,oropharyngeal leak pressure （OLP）,and inspiratory peak airway pressure under positive pressure ventilation at the corresponding cuff volume as indicated above were recorded.Second,the enrolled patients were randomly allocated into minimum effective cuff inflating volume group （MC） and routine care （RC） group in the study 2.The minimum effective cuff inflating volume was applied and maintained in MC group,whereas the cuff volume was inflated with half of the maximum cuff inflating volume recommended by manufacturer in RC group throughout the surgical procedure and stay in postanesthesia care unit prior to LMA removal.The incidence of pharyngeal complications at 0,2,24,and 48 h after removal of LMA and other intra-operative adverse events were also documented.Results：The intracuffpressure varied with the cuff inflating volume in a positive linear correlation manner （Y =11.68X-42
Background：High intracuffpressure can cause severe pharyngeal complications including sore throat or hoarseness after laryngeal mask airway （LMA） removal postoperatively.Though the application of minimum effective cuffinflating volume is suggested to maintain airway sealing and adequacy of ventilation for patients receiving general anesthesia with LMA at lower level of the intracuffpressure,it is currently not a standard care in most of the anesthetic departments.In this study,the minimum effective cuff inflating volume was determined for classic LMA Well LeadTM （Well Lead Medical Co.,Ltd.,China） and its impact on postoperative pharyngeal complications was also explored.Methods：Patients with American Society of Anesthesiologists physical status （Ⅰ-Ⅲ） undergoing the short-duration urological surgery were recruited in this trial.First,the minimum effective cuff inflating volume was determined for size 4 or 5 LMA Well LeadTM in the study 1.Immediately following placement and confirmation of ideal LMA position,the cuff was inflated with 5,7,10 ml of air and up to 30 ml at 5 ml increment.The intracuff pressure,oropharyngeal leak pressure （OLP）,and inspiratory peak airway pressure under positive pressure ventilation at the corresponding cuff volume as indicated above were recorded.Second,the enrolled patients were randomly allocated into minimum effective cuff inflating volume group （MC） and routine care （RC） group in the study 2.The minimum effective cuff inflating volume was applied and maintained in MC group,whereas the cuff volume was inflated with half of the maximum cuff inflating volume recommended by manufacturer in RC group throughout the surgical procedure and stay in postanesthesia care unit prior to LMA removal.The incidence of pharyngeal complications at 0,2,24,and 48 h after removal of LMA and other intra-operative adverse events were also documented.Results：The intracuffpressure varied with the cuff inflating volume in a positive linear correlation manner （Y =11.68X-42
基金
This study was under financial support by the Youth Health Talents Project of Nanjing Municipal Health Bureau and Natural Science Foundation Committee of Jiangsu Province （No. BK2012532）.
