摘要
背景与目的恶性胸腔积液(malignant pleural effusion,MPE)是由原发于胸膜的恶性肿瘤或者是转移至胸膜的恶性肿瘤造成的胸腔积液。对于不明原因的单侧胸腔积液,首要任务是排除或者是确诊恶性胸腔积液。胸腔积液沉淀物是将送检胸腔积液细胞学剩余的胸腔积液进行离心或者是自然静置所获得的细胞块。此技术具有操作简单、有创性小、重复性高、对恶性胸腔积液的诊断率相对较高等特点,在恶性胸腔积液的诊断、治疗等方面起着重要的作用。本文主要从沉淀物的制作方法、免疫组织化学染色检查的鉴别诊断价值、沉淀物的诊断优势及沉淀物行基因检测的临床应用价值等方面来论述胸腔积液沉淀物对恶性胸腔积液的诊断价值。
Malignant pleural effusion （MPE） is due tumor which arises from the mesothelinm or metastases from tumor origniating other sites. In large, for undiagnosed unilateral pleural effusions, the most frequent and important diagnosis to be established or excluded is malignancy： Cell block is prepared from residual fluid which is centrifuged or is naturally sedi- menting to obtain dots at the bottom of the container. The cell block technique is simple, relatively non-invasive, reproducible and has a high yield for malignant plerual effusion. It plays an important role in the diagnosis, guiding the treatment of maligant pleural effusion. Herein, we summarize the technologys which make the cell block, the differential diagnostic value when multiple sections of the cell block are processed for immunhistochemistry, advantages in the diagnosis of malignant pleural ef- fusion, the clinical value ofgene screening in cell block. ＂line aim of this article is to discuss the value ofceU block in diagnosis of maligant pleural effusion.
出处
《中国肺癌杂志》
CAS
CSCD
北大核心
2015年第10期652-655,共4页
Chinese Journal of Lung Cancer
关键词
恶性胸腔积液
沉淀物
诊断价值
Malignant pleural effusion
Cell block
Diagnostic value
