摘要
目的:观察清热除湿内外合治的方法治疗急性痛风性关节炎(湿热蕴结证)的临床疗效。方法:将60例急性痛风性关节炎(湿热蕴结证)患者随机分为治疗组和对照组,每组30例。对照组采用秋水仙碱治疗;治疗组采用竹叶石膏汤加减口服配合痛风清洗剂外洗治疗。两组疗程均为5 d。观察两组临床疗效及治疗前后血尿酸、红细胞沉降率、C-反应蛋白的变化情况。结果:治疗组显效16例,有效12例,无效2例,总有效率为93.33%;对照组显效14例,有效13例,无效3例,总有效率为90.00%。两组比较,差异无统计学意义(P>0.05)。治疗后,两组红细胞沉降率、C-反应蛋白均明显降低(P<0.05),两组比较,差异无统计学意义(P>0.05);治疗组血尿酸明显降低(P<0.05),对照组血尿酸无明显变化(P>0.05),两组比较,差异有统计学意义(P<0.05)。对照组不良反应发生率高于治疗组(P<0.05)。结论:清热除湿法内外合治急性痛风性关节炎(湿热蕴结证)有良好疗效,且无明显不良反应。
Objective：To observe the clinical effect of clearing heat and removing dampness in the treatment of acute gouty arthritis.Methods：60 cases of acute gouty arthritis were randomly divided into a treatment group and a control group,30 cases in each.The control group was treated with colchieine;while the treatment group with modified Zhuye Shigao Tang （ 竹叶石膏汤 ） combined with cleaning agent for gout.They were treated for 5 days.The clinical efficacy and the changes of blood uric acid,erythrocyte sedimentation rate,and C- reactive protein of the two groups were compared.Results：In the treatment group,16 cases were markedly effective,12 cases were effective,and 2 cases were ineffective,the total effective rate being 93.33%;while in the control group, 14 cases were markedly effective, 13 cases were effective,and 3 cases were invalid,the total effective rate being 90%.There was no significant difference between the two groups （ P 〉 0.05 ） .After treatment,the erythrocyte sedimentation rate and C- reactive protein in the two groups significantly decreased （ P 〈 0.05 ） ,and the difference was not statistically significant （ P 〉 0.05 ） ;the blood uric acid was significantly lower in the treatment group （ P 〈 0.05 ） ,and not obvious in the control group （ P 〉 0.05 ） ,difference between them being statistically significant （ P 〈 0.05 ） .The incidence of adverse reactions in the control group was higher than that in the treatment group （ P 〈 0.05 ） .Conclusion：Method of clearing heat and removing dampness has a good curative effect to treat acute gouty arthritis,safety and with no obvious adverse reactions.
出处
《风湿病与关节炎》
2015年第10期17-20,共4页
Rheumatism and Arthritis
关键词
急性痛风性关节炎
湿热蕴结证
清热除湿法
内外合治
acute gouty arthritisdamp-heatsyndrome
clearing heat and remov-ing dampness
exterior and interior treatment
