摘要
目的：分析垂体瘤患者临床特征。方法：统计428例垂体瘤患者的性别、年龄、主要临床症状、影像学诊断、手术方式及并发症,比较术前诊断及术后病理诊断的结果差异。结果：男∶女为1.05∶1,41-50岁发病比例最大（27.80%）,其次为31-40岁（23.60%）;首发症状头痛、头晕、呕吐比例最大183例（42.76%）,其次视物模糊、视力下降126例（29.44%）;大腺瘤比例为（85.63%）、巨大腺瘤为（7.61%）;肿瘤大小为0.4-7.7 cm;MRI诊断率（56.9%）高于CT（30.4%）;经蝶入路垂体瘤切除术患者比率（65.71%）高于行经颅入路垂体瘤切除术患者（34.29%）,但并发症比例（37.96%）低于经颅入路垂体瘤切除术（58.4%）,P〈0.05;手术前后诊断符合率以肾上腺皮质激素（ACTH）瘤最高（90%）,其次无功能腺瘤仅33.63%,差异最大为生长激素（GH）瘤,符合率仅6.78%。结论：垂体瘤中PRL瘤最常见,经蝶入路垂体瘤切除术是主要手术方式,ACTH瘤术诊断符合率最高。
Objective： To discuss clinical features of patients with pituitary tumor. Methods： A total of 428 patients with pituitary tumor resection were selected,and collecting information including gender,age,clinical features,imaging test results,surgery mode and complications,comparing differences between pre-surgery diagnosis and post-surgery pathological diagnosis. Results： Male： female was 1. 05 ∶ 1,and with respect to the age,the pituitary tumor occurred mostly in 41 - 50 years old（ 27. 8%）,next to 31 - 40 years old（ 23. 60%）; the proportion of large adenomas and giant adenomas was 85. 63% and 7. 61% respectively; the size of the tumor was 0. 4 - 7. 7 cm; MRI diagnostic rate（ 56. 9%） was higher than CT（ 30. 4%）; the ratio of patients accepting pituitary tumor resection made by transphenoidal（ 65. 71%） was higher than transcranial（ 58. 4%）,while the postoperative complication of pituitary tumor resection by transphenoidal approach accounted for 37. 96%,which was significantly lower than the transcranial approach of 58. 04%（ P〈0. 05）. The highest coincidence rate of diagnosis before and after operation was the ACTH adenomas（ 90%）,second was no functional adenoma（ 33. 63%）,the biggest difference was GH tumor,with a rate of only 6. 78%. Conclusion： Prolactinoma is the most common type tumor. Transphenoidal approach is major operation mode,and the highest coincidence rate of diagnosis is ACTH adenomas.
出处
《贵阳医学院学报》
CAS
2015年第11期1223-1225,共3页
Journal of Guiyang Medical College
关键词
垂体瘤
临床症状
诊断
手术后并发症
手术方式
pituitary tumor
clinical symptom
diagnosis
postoperative complications
operation mode
