摘要
目的:研究血脂与血尿酸浓度变化在老年脂肪肝患者诊断中的价值。方法:选取我院三年来健康体检时确诊为脂肪肝患者的80例为观察组,体检结果为健康正常人的80例为对照组。测定两组总胆固醇、甘油三酯、血尿酸、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇的值,将检测结果进行对比。结果:两组检测结果对比,观察组的总胆固醇高于对照组的(x2=11.358,P=0.015);观察组的甘油三酯值高于对照组(x2=7.456,P=0.035);观察组中的血尿酸,高于对照组值(x2=9.875,P=0.029)、低密度脂蛋白胆固醇的值,高于对照组(x2=12.037,P=0.013),高密度脂蛋白胆固醇低于对照组(x2=5.149,P=0.041)。在轻、中、重度三组脂肪肝患者中,中度脂肪肝患者的总胆固醇、甘油三酯、血尿酸、低密度脂蛋白含量高于轻度脂肪肝患者,高密度脂蛋白含量低于轻度脂肪肝患者,P<0.05,差异有统计学意义;重度脂肪肝患者的总胆固醇、甘油三酯、血尿酸、低密度脂蛋白含量高于中度脂肪肝患者,高密度脂蛋白含量低于中度脂肪肝患者,P<0.05,差异有统计学意义。结论:脂肪肝病变程度越大,脂肪肝患者总胆固醇、甘油三酯、血尿酸、低密度脂蛋白胆固醇的值越高,高密度脂蛋白胆固醇的值越低,血脂与血尿酸浓度变化可作为诊断脂肪肝疾病的依据,可实现早发现、早治疗,值得应用。
Objective： To investigate the diagnosis value of the changes of blood lipids and blood uric acid concentration in elderly patients with fatty liver. Methods： 80 cases with fatty liver in our hospital were the observation group, while 80 health and normal cases were the control group. The total cholesterol, triglycerides, uric acid, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol of two groups was detected and compared. Results： The total cholesterol of observation group was higher than the control group（x2=11.358, P=0.015）; the triglycerides of observation group was higher than the control group（x2=7.456,P=0.035）; the uric acid of observation group was higher than the control group（x2=9.875,P=0.029）; the low-density lipoprotein cholesterol of observation group was higher than that of the control group（x2=12.037,P=0.013）, the high-density lipoprotein cholesterol of observation group was lower than the control group（x2=5.149,P=0.041）, which had significant differences（P〈0.05）. In comparison of blood lipids and blood uric acid in the groups of mild, moderate and severe fatty liver, the cholesterol, triglycerides, uric acid and low-density lipoprotein of moderate group were higher than that of mild group, the high-density lipoprotein was lower than that of mild group; the value of cholesterol, triglycerides,uric acid and low-density lipoprotein in severe groups were the highest and the value of high-density lipoprotein was the lowest in three groups, and there were significantly statistical differences between any two groups（P〈0.05）. Conclusions： The patients with greater degree of fatty liver had higher level of the total cholesterol, triglycerides, uric acid, low-density lipoprotein cholesterol, and the lower high-density lipoprotein cholesterol, suggesting that the lipids and uric acid concentration could be used as a basis for the diagnosis of fatty liver disease, which could achieve early detection and early treatment and worth of clinic applicati
出处
《现代生物医学进展》
CAS
2015年第27期5333-5335,5339,共4页
Progress in Modern Biomedicine
关键词
脂肪肝
血脂
血尿酸
Fatty liver
Blood lipids
Blood uric acid
