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胶原纤维在皮肤光老化进程中的变化 被引量:2

The change of collagen fibers in the process of cutaneous photoaging
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摘要 目的观察随着年龄增长,胶原纤维在光暴露皮肤和光保护皮肤中的变化,探讨紫外线对皮肤胶原纤维的影响。方法取(9-78)岁正常皮肤标本其30例,采用VG法染色并观察结果。结果与青少年皮肤的胶原纤维染色结果相比,中老年人皮肤的光暴露和光保护部位的胶原纤维均表现为减少,但光暴露部位胶原纤维的减少更明显。结论长期紫外线照射.可能造成皮肤胶原纤维减少,从而皮肤出现皱纹、松弛的老化表现。 Objective To observe the change of collagen fibers in the exposure and non-exposure skin at different ages, and to investigate the influence of UV on collagen fibers of skin. Methods Skin specimens of 30 patients (9- 78y) were stained with VG staining method for collagen fibers and observed. Results Compared with adolescent, collagen fibers of middle and old aged decreased in both exposure and non-exposure skin, and exposure skin were significantly reduced. Conclusion Long-term ultraviolet radiation would reduce the content of collagen fibers, and caused the formation of skin wrinkles.
出处 《皮肤病与性病》 2015年第5期249-251,共3页 Dermatology and Venereology
基金 山西省回国留学人员科研资助项目(编号:2011-099)
关键词 光老化 胶原纤维 VG染色 Photo aging Collagen fibers VG staining
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