摘要
目的:为合理使用抗菌药物提供参考。方法:从北京、天津、上海、杭州、广州、成都六地区三级医院中选择69家作为样本医院,抽取其2009-2013年抗菌药物的采购与门诊使用数据,从抗菌药物占全部化学药采购金额比例、化学药销售金额前80%药品中抗菌药物的个数和品种数、门诊处方抗菌药物使用率、门诊抗菌药物处方中两种及以上抗菌药物联用百分率以及各种类抗菌药物使用比例等方面进行分析。结果:平均抗菌药物占化学药采购金额比例从2009年的20.97%下降至2013年的14.17%,化学药销售金额前80%药品中抗菌药物的个数从2009年的43个下降至2013年的34个,门诊处方抗菌药物平均使用率从2009年的23.22%下降至2013年的16.11%,以上指标比较差异均有统计学意义(P<0.05)。平均抗菌药物的品种数从2009年的78种下降至2012年的54种(P<0.05),但是2013年又回升至66种;门诊抗菌药物处方中两种及以上抗菌药物联用百分率从2009年的9.02%下降至2012年的7.35%(P<0.05),2013又回升至12.89%;门诊抗菌药物处方中抗菌药物注射剂使用率各年度没有明显的变化;同时分别对六地区三级医院各种类抗菌药物的使用情况进行分析,头孢菌素类药物一直排在第1位,几乎是总抗菌药物使用的一半,但比例有下降趋势,而特殊使用级抗菌药物使用率则逐年上升。结论:经过3年抗菌药物专项整治,北京等六地区抗菌药物使用情况整体上有了明显改进,但个别指标改善不大,某些指标2013年有反弹,因此此项工作需要建立持续督导长效机制。
OBJECTIVE:To provide reference for rational use of antibacterials. METHODS:Taking 69 hospitals of Beijing,Tianjin,Shanghai,Hangzhou,Guangzhou,Chengdu as samples,the data about the purchase and application of antibacterials in outpatient department were collected during 2009 to 2013,and analyzed in terms of the proportion of the amount of antibacterials in all chemical drugs,the number of antibacterials among top 80% chemical drugs in the list of consumption sum and their varieties number,the utilization rate of antibacterials in outpatient prescription,the percentage of two and more antibiotics combination in outpatient antibiotics prescriptions,the proportion of antibiotics use,etc. RESULTS:The proportion of average purchase amount of antibacterials in chemical drugs decreased from 20.97 % in 2009 to 14.17 % in 2013;the number of antibacterials among top80% chemical drugs in the list of consumption sum decreased from 43 in 2009 to 34 in 2013;the average utilization rate of outpatient antibacterials decreased from 23.22 % in 2009 to 16.11 % in 2013;there was statistical significance(P〈0.05). The varieties of antibacterials decreased from 78 kinds in 2009 decreased to 54 kinds in 2012(P〈0.05),but rise to 66 kinds in 2013;the percentage of two and more antibacterials combination in outpatient antibacterials prescriptions decreased fron 9.02% in 2009 to7.35% in 2012(P〈0.05),rise to 12.89% in 2013. The utilization ratio of antibacterials injection in outpatient antibacterials prescriptions had no significant change. The utilization of antibacterials in tertiary hospitals from 6 districts was analyzed;cephalosporin had ranked the first place,and almost occupied half part of antibacterials but declined;the utilization rate of antibacterials for special use was on the rise. CONCLUSIONS:After 3 years of antibacterials special rectification,and the utilization of antibacterials in 6 districts as Beijing have been improved significantly;however,several index have little improvements,and some rebou
出处
《中国药房》
CAS
北大核心
2015年第29期4041-4044,共4页
China Pharmacy
关键词
抗菌药物
临床应用
专项整治
合理用药
Antibacterials
Clinical application
Special rectification
Rational drug use