摘要
目的探讨腹部肿瘤患者麻醉中七氟醚饱和状态后降低氧流量的效果。方法 40例腹部肿瘤患者,拟在七氟醚吸入全身麻醉联合硬膜外麻醉下手术。潮气量(TV)设置为8 ml/kg,I:E=1:1.5,呼吸频率(RR)=10 bpm,新鲜气体流量(FGF)=分钟通气量(MV),设定浓度(Fd)为2.4%vol,呼气末浓度(Fet)达到峰值10 min后,记录吸入浓度(Fi)的数值。将FGF/MV从1降低到0.4,10 min内每隔1 min记录Fi和Fet的数值;然后将FGF/MV从0.4降低到0.3,同样方法记录Fi和Fet;最后将FGF/MV从0.3降低到0.2,同样方法记录Fi和Fet的数值。结果 Fet达到峰值后,降低FGF/MV引起Fi轻度下降;相对于起始状态,在2 min和10 min时略有下降,但差异均无统计学意义(P>0.05),呼气末吸入浓度可以稳定在1.7%vol。结论在对肿瘤患者进行麻醉时,在七氟醚吸入麻醉达到饱和状态后降低流量具有很好的效果,具有良好的循环呼吸稳定性。
Objective To investigate effect of reducing oxygen flow rate in sevoflurane saturation of abdominal tumor patients. Methods A total of 40 abdominal tumor patients received operation under sevoflurane inhalation anesthesia combined with epidural anesthesia. Tidal volume（TV） was 8 ml/kg, I ：E=1 ：1.5, respiratory rate（RR）=10 bpm, fresh gas flow（FGF）=minute ventilation（MV）, concentration set（Fd） was 2.4% vol, inspired concentration（Fi） was recorded after 10 min of end tidal concentration（Fet） peak. Fi and Fet were recorded in every 1 min during 10 min from reduced FGF/MV from 1 to 0.4, from 0.4 to 0.3, and from 0.3 to 0.2. Results After peak of Fet, reduced FGF/MV led to slightly reduced Fi, which was also reduced in 2 min and 10 min in the comparison with initial state. Their differences had no statistical significance（P〉0.05）. End tidal inspired concentration could be stabilized at 1.7% vol. Conclusion In anesthesia for tumor patients, reducing oxygen flow rate in sevoflurane saturation can provide excellent effect and good stability in circular respiration.
出处
《中国实用医药》
2015年第25期23-24,共2页
China Practical Medicine
关键词
腹部肿瘤
麻醉
七氟醚
饱和状态
氧流量
Abdominal tumor
Anesthesia
Sevoflurane
Saturation
Oxygen flow rate
