摘要
目的观察前列地尔联合丹红注射液治疗老年人下肢动脉硬化性闭塞症的临床疗效。方法选择在2013年9月~2014年11月在本院就诊的100例已明确诊断为下肢动脉硬化性闭塞症的老年人,随机抽取60例单用前列地尔治疗的患者作为对照组,余40例患者加用丹红注射液作为治疗组。对照组单用前列地尔(1 mL:5μg)10μg入0.9%Nacl 100 mL;治疗组在对照组基础上加用丹红注射液(10 mL)30 mL入0.9%Nacl 250 mL,两组均每日治疗1次,14 d为1个疗程,连用2个疗程,结束后根据Rutherford分期^([1])、踝肱指数进行疗效评估。结果两组在治疗后临床症状均好转,且治疗组总有效率高于对照组(P<0.05);两组治疗后踝肱指数较治疗前均明显改善,且治疗组明显优于对照组(P<0.05),两组均未发现肝肾功能损害,无严重不良反应发生。结论前列地尔联合丹红注射液治疗老年人下肢动脉硬化性闭塞症的临床疗效显著。
Objective To evaluate the clinical efficacy of prostaglandin Seoul Danhong injection therapy combined with arteriosclerosis obliterans of the elderly. Methods From September 2013 to November 2014 in our Hospital, 100 cases has been diagnosed as arteriosclerosis obliterans elderly, patients were randomly selected single-use alprostadil treat- ment of 60 cases as control group, more than 40 patients plus danhong injection as a treatment group. The control group was treated with alprostadil （1 mL：5 micrograms） 10 μg into 0.9% Nacl 100 mL; the treatment group danhong injection were based on （10 mL） 30 mL into 0.9% Nacl 250 mL, both groups every Day 1 treatment, 14 days a course of treatment, once every two courses, according to the Rutherford stage , the ankle-brachial index for efficacy evaluation. Results The two groups in clinical symptoms were improved, and the total effective rate was higher （P〈0.05）; the two groups after treatment, before the ankle-brachial index were significantly improved compared with the treatment, and the treatment group improved more than the in the control group（P〈0.05）. Conclusion Alprostadil injection in joint clinical efficacy Danhong elderly arteriosclerosis obtiterans significantly.
出处
《中国现代医生》
2015年第28期56-58,共3页
China Modern Doctor
