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Improved microwave-assisted catalyst-free synthesis of9-aryl-5,9-dihydropyrimido[4,5-d][1,2,4]triazolo[1,5-a]pyrimidine-6,8(4H,7H)-dione derivatives

Improved microwave-assisted catalyst-free synthesis of9-aryl-5,9-dihydropyrimido[4,5-d][1,2,4]triazolo[1,5-a]pyrimidine-6,8(4H,7H)-dione derivatives
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摘要 Agreen regioselective synthesis of some new and known 9-aryl-5,9-dihydropyrimido[4,5-d][l,2,4]triazolo[1,5-a]pyrimidine-6,8(4H,7H)-diones has been described via the microwave-assisted one-pot reaction of 3-amino-1H-1,2,4-triazoles,aromatic aldehydes and barbituric acids under solvent- and catalyst-free conditions.This operationally simple procedure is less laborious and provides a better scope than previously reported procedures. Agreen regioselective synthesis of some new and known 9-aryl-5,9-dihydropyrimido[4,5-d][l,2,4]triazolo[1,5-a]pyrimidine-6,8(4H,7H)-diones has been described via the microwave-assisted one-pot reaction of 3-amino-1H-1,2,4-triazoles,aromatic aldehydes and barbituric acids under solvent- and catalyst-free conditions.This operationally simple procedure is less laborious and provides a better scope than previously reported procedures.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2015年第9期1065-1067,共3页 中国化学快报(英文版)
关键词 9-Aryl-5 9-dihydropyrimido[4 5-d] [ 1 2 4]triazolo[1 5-a]pyrimidine- 6 8(4H 7H)-diones Barbituric acids 3-Amino- 1 H- 1 2 4-triazoles Aryl aldehydes Microwave-assisted synthesis 9-Aryl-5,9-dihydropyrimido[4,5-d] [ 1,2,4]triazolo[1,5-a]pyrimidine- 6,8(4H,7H)-diones Barbituric acids 3-Amino- 1 H- 1,2,4-triazoles Aryl aldehydes Microwave-assisted synthesis
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