摘要
目的探讨腹腔脂肪面积(IFA)的CT测量值与胃癌患者手术后短期结局间的关系。方法回顾性分析2010年5月—2011年9月间在上海交通大学医学院附属瑞金医院普外科行经腹胃切除+D2淋巴结清扫术的226例胃癌患者的临床资料。所有患者均于术前经多排螺旋CT(MDCT)扫描测量IFA,根据其中位值将患者分为高IFA组(IFA≥85cm^2,95例)和低IFA组(IFA<85cm^2,131例)。记录并比较两组患者的年龄、性别构成、手术方式、胃癌分期构成、手术时间、胃癌周围组织中淋巴结检出数目、术中出血量,以及术后早期并发症发生情况。结果两组间患者的年龄、性别构成、胃切除方式、胃癌分期构成、手术时间和术中出血量的差异均无统计学意义(P值均>0.05)。低IFA组患者的胃癌周围组织中淋巴结检出数目显著多于高IFA组(P<0.05)。共27例患者(11.9%,27/226)发生术后早期并发症。高IFA组术后并发症发生率为15.8%(15/95),低IFA组为9.2%(12/131),两组间差异无统计学意义(P>0.05)。结论经MDCT测量的IFA能较好地反映腹腔内脂肪分布情况,IFA低的胃癌患者胃癌周围组织中淋巴结检出数目较多。
Objective To explore the relationship between the intra-abdominal fat area （IFA） and early clinical outcomes of surgical treatment in gastric cancer patients. Methods A total of 226 consecutive gastric cancer patients who underwent a potentially curative gastrectomy and D2 lymphadenectomy between May 2010 and September 2011 were included in this retrospective study. According to IFA measured by multi-dector computer tomography （MDCT） scan, the patients were divided into two groups： high IFA group （IFA≥85 cm^2 , n = 95） and low IFA group （IFA〈85 cm^2, n = 131）. Parameters such as age, male/female （M/F） ratio, operation mode, staging of gastric carcinoma, operation time, the number of lymph nodes found in para-tumor tissues, intraoperative blood loss and nonsurgical complications were recorded and compared between groups. Results There were no significant differences in terms of age, M/F ratio, operation mode, staging of gastric carcinoma, operation time or intraoperative blood loss between two groups （all P〉0.05）. The number of lymph nodes found in para-tumor tissues in the low IFA group was significantly more than that in the high IFA group （P〈0.05）. Early complications occurred in 27 patients （11. 9%, 27/226） after surgery. The incidence of postoperative complications was 15.8 % （15/95） in the high IFA group, which was not significantly different from that in the low IFA group （9.2 % [ 12/131], P〉 0.05）. Conclusion More lymph nodes can be detected in gastric cancer patients with low IFA measured by MDCT.
出处
《上海医学》
CAS
CSCD
北大核心
2015年第7期587-589,共3页
Shanghai Medical Journal
基金
上海高校选拔培养优秀青年教师科研专项基金资助项目(Zzjdyx12021)
关键词
胃癌淋巴结清扫
腹腔脂肪面积
多排螺旋CT
Lymph node dissection of gastric cancer
Intra-abdominal fat area
Multi-dector computer tomography
