摘要
目的观察盐酸利托君注射液治疗先兆早产的临床效果及对新生儿的影响。方法选取2013年8月至2014年9月就诊的110例先兆早产患者,根据治疗方法进行分组,对照组给予硫酸镁治疗,试验组给予盐酸利托君注射液治疗。结果试验组患者保胎成功率为96.36%、宫缩显效时间(2.11±0.62)h、延长分娩时间(14.32±10.43)d,显著优于对照组的63.64%、(5.60±1.23)h、(22.13±14.25)d(P<0.05)。试验组新生儿死亡率为1.82%、新生儿出生体重(2 567.4±229.7)g、新生儿阿氏(Apgar)评分(9.3±0.8)分,显著优于对照组的18.18%、(2 140.8±162.3)g、(8.3±0.5)分(P<0.05)。试验组患者用药后不良反应发生率为7.27%,明显低于对照组的32.73%(P<0.05)。结论先兆早产患者应用盐酸利托君注射液治疗的临床效果显著,可有效抑制孕妇宫缩,延长孕妇的妊娠时间,保胎成功率较高且新生儿情况良好,安全可靠。
Objective To study Ritodrine Hydrochloride injection treatment effect of Aura preterm birth and influence on newborn. Methods From August 2013 to September 2013 in our hospital 110 patients with aura premature birth, according to the treatment methods, and in the control group patients were given magnesium sulfate, yet in the experimental group patients were given hydrochloride injection treatment. The clinical efficacy of two groups of patients and effect of newborn was compared. Results in the experimental group spue success rate （96. 36% ）, patients with contractions time （2. 11 ±0. 62） h, the extend time of delivery （14.32 ± 10. 43） d, spue success rate （63.64%）, significantly better than the control group contractions time （5.60± 1.23） h, the extend time of delivery （22. 13 ±14.25） d, statistical significance difference （P 〈 0.05）. Experimental neonatal mortality （1.82%）, neonatal birth weight （2 567.4±229.7） g, newborn Apgar score （9.3 ±0.8） significantly better than control group in neonatal mortality rate （18.18%）, neonatal birth weight （2 140.8± 162. 3） g, newborn Apgar score （8.3±0. 5） points, statistical significance difference （ P 〈 0. 05）. In experimental group incidence of drug adverse reactions （7.27%） after the drug was significantly lower than the control group （32.73%）, the incidence of adverse reactions, statistical significance difference （P 〈 0.05）. Conclusion The clinical effect of Ritodrine Hydroehloride injection on patients is remarkable, effectively restrain pregnant women contractions, extended the pregnant women of pregnancy, spuc success rate is higher, the condition is good, safe and reliable, and can be popularized in clinical application.
出处
《中国药业》
CAS
2015年第19期84-86,共3页
China Pharmaceuticals
关键词
盐酸利托君注射液
先兆早产
硫酸镁
临床效果
新生儿
ritodrine hydrochloride injection
aura preterm birth
magnesium sulfate
clinical effect
newborn
