摘要
胰腺癌干细胞(PCSC)在胰腺癌的发生、发展过程中起着重要作用,且与胰腺癌的耐药、转移机制关系密切。PCSC的表面标志物、分离、鉴定、信号通路、微环境、耐药、转移和靶向治疗等方面的研究,将为临床胰腺癌的治疗提供新的方向。
Pancreatic cancer stem cells （PCSCs） play an important role in the occurrence and development of pancreatic cancer, and are also closely related to the mechanisms for chemotherapy resistance and metastasis of pancreatic cancer. Investigations of PCSCs with regard to their surface markers, isolation, identification, signal pathways, microenvironment, drug resistance, metastasis and targeted therapy may provide a new prospect for the clinical treatment of pancreatic cancer.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2015年第9期1304-1309,共6页
China Journal of General Surgery
基金
国家自然科学基金资助项目(81372628)
关键词
胰腺肿瘤
肿瘤干细胞
综述文献
Pancreatic Neoplasms
Neoplastic Stem Cells
Review
