期刊文献+

儿童危重症患者血液P-选择素与E-选择素的变化

The Blood and E-P-select Element Selection Changes in Children With Critically Disease
下载PDF
导出
摘要 目的分析儿童危重症患者血液P-选择素与E-选择素的变化及与患者病程严重程度及预后的关系。方法挑选在我院进行治疗的危重症患儿30例,作为为研究组,采集患儿的血液,另选取在我院进行其他疾病治疗并留有血液样本的患儿30例,将其归为对照组,将研究组患儿及对照组患儿的血液样本进行P-选择素与E-选择素的检测对比,并比较患儿在急性发作期及恢复期P-选择素与E-选择素浓度,分析其关系。结果对照组患儿的P-选择素与E-选择素明显低于研究组患儿,差异存在统计学意义(P<0.05);急性发作期危重症患儿的P-选择素与E-选择素明显高于恢复期危重症患儿,差异存在统计学意义(P<0.05)。结论儿童危重症患儿的血液P-选择素与E-选择素有显著升高,且P-选择素与E-选择素越高,说明患儿的病情越严重。 Objective To analyze children critically ill patients blood P-select element and the change of the E-select element and relationship with the course of the disease severity and prognosis of patients. Methods Selected 30 critically ill patients as a team in our hospital for treatment, collect the patient's blood, the other selection in our hospital for other diseases treatment and had blood samples of 30 cases of children, to be classified as the control group, the group of children and children with blood samples in the control group (P-compared with the detection of E-select element, and compared with in the acute phase and convalescence and the choice of E-P- select element concentration, analysis of the relationship. Results In the control group with E-P- select element selection for children with significantly lower than the team differences statistically significant (P〈0.05). Acute phase of critically ill children with E-P- select element selection, significantly higher than the recovery critically ill children, differences are statistically significant (P〈0.05).Conelusion Children critically ill children with blood P-select element and E-known as the marked increase in the choice, and the P-choose element with E-select the higher, the more severe the patient.
出处 《中国继续医学教育》 2015年第25期33-35,共3页 China Continuing Medical Education
关键词 儿童危重症 P-选择素 E-选择素 Children critically ill, P-select element, E-select element
  • 相关文献

参考文献3

二级参考文献44

  • 1仇烨,吴杰,房晓祎,林震,吴北燕,蔡若吟,徐小燕,郑虹.P选择素及E选择素在小儿川崎病血管损伤中的作用机制及其意义[J].中华儿科杂志,2004,42(9):688-692. 被引量:17
  • 2刘凌,陈晓红,梁莉红,李结敏.呼吸系统疾病中SE-选择素的临床意义[J].热带医学杂志,2005,5(1):107-108. 被引量:3
  • 3才立云,赵宝春,耿旭.血管黏附分子中选择素结构、功能及其表达的特点[J].中国组织工程研究与临床康复,2007,11(14):2729-2732. 被引量:8
  • 4金虹 梁翊常 等.正常儿童冠状动脉超声心动图研究[J].中华儿科杂志,1988,26:257-259. 被引量:20
  • 5Daiani AS, Taubert KA,Gerber MA,et al. Diagnosis and therapy of Kawasaki disease in children . Circulatian,1993,87:1776-1780. 被引量:1
  • 6Minamino T, Kitakaze M, Sanada S, et al. Increased expression of P-selection on platelets is a risk factor for silent cerebral infarction in patients with atrial fibrillation.Circulation,1998,98:1721-1727. 被引量:1
  • 7Lefer AM,Weyrich AS,Buerke M.Role of selectins,a new family of adhesion molecules,in iachaemiareperfusion injury.Cardiovaac Rea,1994,28:289. 被引量:1
  • 8Weyrich AS,Ma XL,Lefer DJ,et al.In vivo neutralization of Pselection protects feline heart and endothelium in myocardial ischemia and reperfusion injury.J Clin Invest,1993,91:2620. 被引量:1
  • 9Evangelista V, Manarini S, Sideri R, et al. Platelet/polymorphonuclear leukocyte interaction: P-selection triggers protein-tyrosine phosphorylation-dependent CD11B/CD18 adhesion: role of PSGL-1 as signaling molecule. Blood,1999,93: 876-885. 被引量:1
  • 10Takeshita S, Dobashi H,Nakatani K,et al. Circulating soluble selectins in Kawasaki disease. Clin Exp Immunol, 1997, 108:446-450. 被引量:1

共引文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部