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43例食管鳞癌累及野放疗联合化疗的疗效分析 被引量:2

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摘要 目的:探讨食管鳞癌累及野放疗联合化疗的副反应、复发模式、预后因素及疗效。方法回顾性分析Ⅰ~Ⅲ期食管鳞癌患者43例,接受累及野放疗联合化疗,放疗剂量为 DT60Gy/30Fx,化疗方案:“顺铂+氟尿嘧啶”方案11例,“奥沙利铂+替吉奥”方案8例,多西他赛/紫杉醇+顺铂21例,替吉奥单药方案3例。研究放化疗期间副反应、复发模式、预后因素及1、2年生存率。结果患者放化疗期间Ⅲ、Ⅳ级副反应共7例,复发模式为:单纯靶内复发13例(56.5%)、单纯靶外复发1例(4.3%)、单纯远处转移6例(26.1%)、靶内复发伴远处转移2例(8.7%)、靶外复发伴远处转移1例(4.3%),肿瘤 TNM分期是独立的预后因素,1、2年生存率分别为83.2%、69.3%。结论食管鳞癌行累及野放疗联合化疗耐受性好,主要复发模式为靶内复发及远处转移。食管鳞癌放疗照射最佳照射野需要进一步的研究。
出处 《安徽医药》 CAS 2015年第10期1984-1986,共3页 Anhui Medical and Pharmaceutical Journal
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