摘要
季酮酸片段是螺环季酮酸类杀虫杀螨剂的重要的中间体。在现有工艺基础上,采用正丁基锂作为酯交换和环合的碱性试剂,一步制备该中间体,提高了该中间体收率,缩短反应时间,操作更加方便。本工艺适合产业化生产螺环季酮酸类杀虫杀螨剂中间体片段。
Tetronic acid structure is an important intermediates of spirocyclic tetronic acids pesticide. The intermediate was synthesized in one step by applying n-butyl lithium based on current process, which improved yield, shortened reaction time, and worked easily. It is suitable for commercial process of intermediates of spirocyclic tetronic acid pesticide.
出处
《精细与专用化学品》
CAS
2015年第9期36-38,共3页
Fine and Specialty Chemicals
关键词
季酮酸
中间体
正丁基锂
改进
tetronic acids
intermediates, n-butyl lithium
modification
