摘要
目的:了解门诊皮肤科处方超药品说明书用药情况。方法:随机抽取皮肤科门诊处方每月100张,共抽取1 200张处方,含3 247条用药记录。根据药品说明书内容,判断是否超说明书用药,并分析超说明书用药的类型。结果:其中超说明书用药处方208张,占17.33%;超说明书用药记录587条,占18.08%。超说明书用药类型中居前三位的是:超适应症(37.99%)、改变给药途径(26.58%)、超剂量(19.08%)。结论:门诊皮肤科处方中存在超药品说明书用药现象,应强化医疗机构的管理职能,规范医生执业行为,控制超药品说明书用药风险。
Objective: To investigate off-label drug use in outpatient department of dermatology. Methods: A total of 1 200 prescriptions (100 prescriptions/ month) containing 3 247 drug-using records in outpatient department of dermatology were randomly selected. According to the relevant information based on drug instructions, the off-label drug uses were judged and the types of off-la-bel use were analyzed. Results: There were 208 (17. 33% ) off-label drug use prescriptions, involving 587 records (18. 08% ) of the off-label use. Among them, 37. 99% prescriptions were beyond of indications, 26. 58% were changes of the route of administration, and 19. 08% were overdose. Conclusions: The off - label drug use in the department of dermatology is very common. It should strengthen the function of medical institution management to control the risks of the off-label drug use.
出处
《中国民康医学》
2015年第17期83-84,86,共3页
Medical Journal of Chinese People’s Health
基金
2013年川北医学院科研发展计划项目(编号:CBY13-B-QN15)
关键词
超说明书用药
皮肤科
门诊处方
合理用药
Off-label drug use
Department of dermatology
Outpatient prescription
Rational use of drug
