摘要
目的:探讨舒芬太尼复合右(旋)美托嘧啶运用在主动脉瘤腔内隔绝术中的有效性和安全性。方法:选取2010年5月-2013年5月50例主动脉瘤腔内隔绝术患者为研究对象,分成2组,对照组25例,予舒芬太尼复合咪达唑仑,观察组25例,予舒芬太尼合右(旋)美托嘧啶,观察不同时间内在血压、心率、呼吸频率和血氧饱和度等方面的变化情况,观察不良反应。结果:T0、T1、T2、T3、T4、T5、T6在RR、血氧饱和度上比较差异均无统计学意义(P>0.05)。在T0、T1、T2、T3SBP、DBP、HR、Narcotrend指数上比较差异无统计学意义(P>0.05),在T4、T5、T6SBP、DBP、HR、Narcotrend指数上比较差异有统计学意义(P<0.05);对照组躁动、呛咳、恶心呕吐、肌紧张、上呼吸道梗阻、呼吸抑制发生率分别为12%、24%、8%、20%、8%、16%;观察组分别为0、4%、4%、0、0、4%,两组比较差异有统计学意义(P<0.05)。结论:舒芬太尼复合右(旋)美托嘧啶能满足主动脉瘤腔内隔绝术麻醉要求,镇痛效果好,呼吸影响性低,无明显不良反应。
Objective：To investigate efficacy and safety of sufentanil dexmedetomidine in endovascular aortic an-eurysm. Methods：All 50 cases of aortic aneurysm endovascular patients were divided into two groups,25 cases in the control group given sufentanil midazolam,the observation group,to Shufen fentanyl given dexmedetomidine together, observe internal blood pressure at different times,heart rate,respiratory rate and oxygen saturation. Results：T0 ,T1 , T2 ,T3 ,T4 ,T5 ,T6 in the RR,oxygen saturation showed no significant difference（P 〉 0. 05）;and in T0 ,T1 ,T2 ,T3 SBP,DBP,HR,Narcotrend index was no significant difference（P 〉 0. 05）,in T4 ,T5 ,T6 SBP,DBP,HR,Narcotrend index difference was statistically significant（P 〈 0. 05）. The adverse reactions：in the control group restlessness,cho-king cough,nausea,vomiting,muscle tension,upper airway obstruction,respiratory depression rates were 12% ,24% , 8% ,20% ,8% ,16% ,observation group were 0 ,4 % ,4 % ,0 ,0 ,4 % ,the difference was statistically significant （P 〈 0. 05）. Conclusion：Sufentanil dexmedetomidine will be able to meet the endovascular aortic aneurysm requires anesthesia,analgesic effect,respiration is low,no significant adverse reactions.
出处
《现代肿瘤医学》
CAS
2015年第19期2825-2827,共3页
Journal of Modern Oncology
基金
邢台市科学技术研究与发展计划课题(编号:2012ZZ031-12)
