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重症颅脑损伤合并应激性高血糖患者的血糖控制 被引量:2

The Blood Glucose Control in Patients With Severe Craniocerebral Injury Complicated With Stress Hyperglycemia
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摘要 目的探讨重症颅脑损伤应激性高血糖患者目标指导下的有效血糖控制的临床疗效。方法对104例急性重度颅脑损伤应激性高血糖患者,采用目标指导下的血糖控制方案,应用胰岛素泵连续静脉注射普通胰岛素治疗,进行回顾性分析。所有病例分为2组,Ⅰ组为目标指导下有效血糖控制,血糖控制目标:4.1~8.1 mmol/L,Ⅱ组为强化血糖控制,血糖控制目标:4.1~6.1 mmol/L。结果Ⅰ组恢复良好和中度残障的病例占总病例数的71.0%,Ⅱ组为57.1%,两组比较具有差异,P〈0.05。结论重症颅脑损伤应激性高血糖患者应用胰岛素泵连续静脉注射普通胰岛素治疗,血糖控制目标:4.1~8.1 mmol/L能够降低重症颅脑损伤患者的死亡率,减少并发症的发生,提高生存质量。 ObjectiveTo investigate effective blood glucose control in patients with severe brain injury combined stress hyperglycemia .Methods 104 patients with acute severe brain injury and stress hyperglycemia, using glucose control program under the target guide of insulin pump continuous intravenous regular insulin therapy. Al patients were divided into 2 groups,Ⅰgroup effectively controled blood glucose under the target guidance,blood glucose control targets was 4.1~8.1 mmol/L. Ⅱ group was intensive glucose control,blood glucose control targets was 4.1~6.1 mmol/L.ResultsⅠgroup’good recovery and moderate disability cases accounted for 71.0% of the total number of cases,Ⅱ group was 57.1%. The two groups had significant difference,P〈 0.05.Conclusion Severe brain injury patients with stress hyperglycemia,blood glucose control targets at 4.1~8.1 mmol / L, can reduce mortality,reduce complications and improve the quality of life.
作者 李云峰
出处 《中国卫生标准管理》 2015年第24期65-66,共2页 China Health Standard Management
关键词 重症颅脑损伤 应激性高血糖 目标指导下的有效血糖控制 Severe craniocerebral injury Stress hyperglycemia Effective blood glucose control under the target guidance
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  • 1叶光福,杨博.ICU的血糖控制[J].麻醉与监护论坛,2010,17(2):103-106. 被引量:2
  • 2Van den Berghe G, Wouters PJ, Bouillon R, et al. Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control [J ] . Crit Care Med, 2013, 31 ( 2 ) : 359-366. 被引量:1

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