摘要
目的总结糖尿病和非糖尿病肝脓肿患者的临床数据及病原学结果，为更好地认识肝脓肿、改进治疗方案提供参考依据。方法回顾性分析细菌性肝脓肿112例，按是否有糖尿病分为糖尿病组和非糖尿病组。对两组病例的年龄、培养阳性率、病原菌分布特点进行比较。结果糖尿病组71例（63．4％），非糖尿病组41例（36．6％），两组年龄差异有统计学意义（P〈0．01）。两组在男女比例、进行介入或外科干预、行血培养或引流液培养比率、培养阳性率等方面差异无统计学意义；培养出的病原菌方面，肺炎克雷伯菌（KP）在两组均排第一位，糖尿病组的KP出现率明显高于非糖尿病组（95．0％vs68．2％，P〈0．01）。结论糖尿病与非糖尿病肝脓肿患者的病原菌分布差异有统计学意义，非糖尿病的肝脓肿患者在初始经验性治疗时选择的抗生素应更加广谱。
Objective The present study aims to investigate the characteristics of liver abscess and improve the treatment by reviewing the clinical data and bacterial culture results of pyogenic liver abscess. Methods By reviewing the clinical data of 112 pyogenic liver abscess, the patients were divided into two groups according to the diagnosis of diabetes or not. Age, positive culture ratio, pathogenic bacteria between the two groups were compared. Results Diabetic group （DM） contained 71 cases （63.4%）, and non -diabetic group （NDM） contained 41 cases （36. 6%）. There were significant difference in age （ P 〈 0.01 ）, no significant difference in gender, drainage ratio, culture examination ratio and positive bacterial culture. Among the results of the cultured bacteria, Klebsiella Pneumonia （KP） is the most in both groups, but ratio of KP is significant higher in DM group than in NDM group （95.0% vs. 68.2%, P 〈 0.01 ）. Conclusion There is significant difference in the cultured bacteria between diabetic and non -diabetic pyogenic liver abscess patients. When initially choosing antibiotics, the choice for the non - diabetic liver abscess patient should be more broad - spectrum.
出处
《中国急救医学》
CAS
CSCD
北大核心
2015年第9期808-810,共3页
Chinese Journal of Critical Care Medicine
关键词
肝脓肿
糖尿病
肺炎克雷伯菌
病原菌
Pyogenic liver abscess
Diabetes
Klebsiella pneumoniaePathogenic bacteria
