1Torre LA, Bray F, Siegel RL, et al. Global Cancer Statistics,2012 [J]. CA Cancer J Clin, 2015,65(2) :87-108. 被引量：1
2Van den Beuken-van Everdingen MH, de Rijke JM, Kessels AG, et al. Prevalence of pain in patients with cancer : a systematic review of the past 40 years [ J ]. Ann Oncol, 2007,18 ( 9 ) : 1437 - 1449. 被引量：1
3Caraceni A, Hanks G, Kaasa S, et al. Use of opioid analgesics in the treatment of cancer pain : evidence-based recommendations from the EAPC[J]. Lancet Oncol,2012,13(2) :e58-e68. 被引量：1
4Radbruch L, Loick G, Schulzeck S,et al. Intravenous titration with morphine for severe cancer pain: report of 28 cases [ J ]. Clin J Pain, 1999,15(3) :173-178. 被引量：1
5Kumar KS, Rajagopal MR, Naseema AM. Intravenous morphine for emergency treatment of cancer pain [ J ]. Palliat Med, 2000,14 ( 3 ) : 183-188. 被引量：1
6Mereadante S, Villari P, Ferrera P,et al. Rapid titration with intra- venous morphine for severe cancer pain and immediate oral conver- sion [ J]. Cancer,2002,95 ( 1 ) :203-208. 被引量：1
7Eisner F, Radbruch L, Loick G, et al. Intravenous versus subcutane- ous morphine titration in patients with persisting exacerbation of cancer pain [ J ]. Palliat Med,2005,8 (4) :743-750. 被引量：1
8Harris JT, Suresh Kumar K, Rajagopal MR. Intravenous morphine for rapid control of severe cancer pain [ J ]. Palliat Med, 2003,17 ( 3 ) :248-256. 被引量：1
9Klepstad P, Kaasa S, Jystad A,et al. Immediate-or sustained-release morphine for dose finding during start of morphine to cancer pa- tients: a randomized, double-blind trial [ J ]. Pain, 2003, 101 (1-2) :193-198. 被引量：1
10Mereadante S. Opioid titration in cancer pain: a critical review [ J ]. Eur J Pain ,2007,11 ( 8 ) :823-830. 被引量：1
5National Comprehensive Cancer Network. Clinical prac- tice guideline in oncology: adult cancer pain[EB/OL]. (2016-03-17)[2016-04-09]. https ://www.nccn.org/store/ login/login.aspx?ReturnURL=https://www.nccn.org/profe- ssionals/physician_gls/pdf/pain.pdf. 被引量：1
6Hwang IC, Park JY, Myung SK, et al. OPRM1 A118G gene variant and postoperative opioid requirement: a sys- tematic review and meta-analysis[J].Anesthesiology, 2014, 121(4):825. 被引量：1
7Ren ZY, Xu XQ, Bao YP, et al. The impact of genetic variation on sensitivity to opioid analgesics in patients with postoperative pain: a systematic review and me- m-analysis[J]. Pain Physician, 2015,18(2) : 131. 被引量：1
8Zhang F, Liao Q, Li L, et al. The correlation between post-operative fentanyl requirements and μ-opioid recep- tor gene A118G polymorphism in patients undergoing rad- ical gastrectomy[J]. Exp TherMed, 2013,5(4), 1 147. 被引量：1
9Campa D, Gioia A, Tomei A, et al. Association of AB- CB1/MDR1 and OPRM1 gene polymorphisms with mor- phine pain relief[J]. Clin Pharmaeol Ther, 2008,83 (4) : 559. 被引量：1
10Gong XD, Wang/Y, Liu F, et aL Gene polymorphis of OPRMI A118G and ABCBI C3435T may influence opi- oid requirements in Chinese patients with cancer pain[J]. Asian Pacific J Cancer Prevent, 2013,14(5) :2 937. 被引量：1
