摘要
目的探讨全自动血细胞分析仪Sysmex XE-2100检测外周血所得白细胞研究性参数对初诊乙型肝炎患者的临床意义。方法选取感染科门诊96例初诊乙型肝炎患者(观察组)和100例同期健康体检人群(对照组)作为研究对象。对上述人群进行相关指标的检测,如乙型肝炎病毒DNA(HBV-DNA)、乙型肝炎表面抗原(HBsAg)、天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT),淋巴细胞参数Lymph-Y、Lymph-X,中性粒细胞参数Neut-Y、Neut-X,记录检测结果并通过统计学软件SPSS19.0进行统计学数据处理、分析。结果观察组与对照组比较,Lymph-X、Neut-Y、Neut-X差异无统计学意义(P>0.05),而HBV-DNA、HBsAg、AST、ALT、Lymph-Y各检测指标两组间比较,差异有统计学意义(P<0.05),并且参数Lymph-Y与HBVDNA(r=0.160,P=0.026)和HBsAg(r=0.149,P=0.037)均呈正相关。结论初诊乙型肝炎患者外周血淋巴细胞参数Lymph-Y高于健康人群,可能是一个潜在的用于鉴别诊断的指标。
Objective To study the clinical significance of leukocyte parameters measured by using automatic blood cell analyzer SysmexXE‐2100inpatientsnewlydiagnosedwithhepatitisB.Methods 96patientsnewlydiagnosedwithhepatitisB（observation group） and 100 people who underwent healthy examination during the same period（control group） were recruited in the study .Rel‐ative indicators were measured for the people mentioned above ,such as the DNA of Hepatitis B virus（HBV‐DNA） ,Hepatitis B sur‐face antigen（HBsAg） ,aspartate aminotransferase（AST ） ,alanine aminotransferase（ALT ） ,lymphocytes parameters Lymph‐Y and Lymph‐X ,neutrophils parameters Neut‐X and Neut‐Y .The test results were recorded and statistically analyzed by using software SPSS19 .0 .Results The differences of Lymph‐X ,Neut‐Y and Neut‐X were not statistically significant compared between observa‐tion group and control group（P〉0 .05） ,while the differences of HBV‐DNA ,HBsAg ,AST ,ALT and Lymph‐Y were statistically significant compared between the two groups（P〈0 .05） .In addition to that ,the parameter Lymph‐Y was positirely correlated with HBV‐DNA（r=0 .160 ,P=0 .026） and HBsAg（r=0 .149 ,P=0 .037） .Conclusion The peripheral blood lymphocytes parameter Lymph‐Y of patients newly diagnosed with hepatitis B is higher than healthy people ,which makes it possible to become an indicator for differential diagnosis .
出处
《国际检验医学杂志》
CAS
2015年第17期2524-2525,2528,共3页
International Journal of Laboratory Medicine
关键词
乙型肝炎
病毒感染
淋巴细胞
散点图
hepatitis B
virus infection
lymphocytes
scatter diagram
