摘要
目的观察盐酸左西替利嗪口服液治疗儿童慢性荨麻疹的疗效。方法将68例慢性荨麻疹的病例用随机单盲法分为治疗组和对照组：治疗组,33例,口服盐酸左西替利嗪口服液,2~6岁5 ml,6~12岁10 m L,每日1次;对照组,35例,马来酸氯苯那敏片组,每日0.35 mg/kg,分3次服用。根据治疗前、治疗后7天及14天随访的总积分评价疗效。结果 1周后,治疗组与对照组总有效率分别为96.97%和85.71%,经检验其差异有统计学意义（P〈0.05）;2周后的总有效率分别为93.93%及82.85%,差异无统计学意义（P〉0.05）。结论盐酸左西替利嗪口服液治疗儿童慢性荨麻疹起效快、疗效好、副作用少、用药简便、儿童依从性好,值得在临床上推广。
Objective To observe the curative effect of levocetirizine hydrochloride oral solution in the treatment of children withchronic urticaria. Method 68 children with chronic urticaria were randomly divided into the treatment group and the control group. Thetreatment group（33 cases） were treated with oral levocetirizine hydrochloride oral solution, 5 ml for children aged 2 to 6 and 10 ml forchildren aged 6 to 12, once a day. The control group（35 cases） were treated with chlorphenamine maleate tablets, 0.35 mg / kg per day,three times a day. According to the total integral of the follow-ups of 7 days and 14 days after treatment respectively, the curative effectwas evaluated. Results In 7 days after treatment, the effective rate was 96.97% in the treatment group and 85.71% in the controlgroup,showing there was significant difference between the two groups（P 0.05）. In 14 days after treatment, the effective rate was93.93% in the treatment group and 82.85% in the control group, the difference between the two groups was not statistically significant.Conclusion Levocetirizine hydrochlorde oral solution treatment of children with chronic urticaria has a fast onset,good curative effectand less side effects, simple process, and good treatment compliance in children, which contributes to it well worthy of clinical popular-ization.
出处
《山西大同大学学报（自然科学版）》
2015年第4期58-60,共3页
Journal of Shanxi Datong University(Natural Science Edition)
关键词
盐酸左西替利嗪口服液
儿童慢性荨麻疹
临床疗效
levocetirizine hydrochloride oral solution
chronic urticaria in children
clinical efficacy
