摘要
目的探讨苯丙酮尿症患儿特殊饮食治疗后智力发育情况以及与开始治疗时间和依从性的关系。方法采用0~6岁儿童神经心理发育量表对2002~2011年潍坊市新生儿疾病筛查中心确诊的60例PKU患儿和60例正常儿童进行测查。结果开始治疗年龄〈40天组与开始治疗年龄〉40天组比较,在适应性、大运动、语言3个能区差异有统计学意义（P〈0.05）,而在精细运动、个人-社交2个能区差异无统计学意义（P〉0.05）。正常儿童组与饮食配合组智力发育差异无统计学意义（P〉0.05）,饮食配合组与不配合组患儿智力发育差异有统计学意义（P〈0.05）。结论经饮食控制的PKU患儿智力发育正常,治疗的起始时间以及严格的饮食治疗对于PKU患儿至关重要。
Objective：To explore the relation of mental development and intinial treatment time and cooperativity in PKU children by after special food and drink treatment. Methods：There were 60 cases PKU patients（diagnosed through neonatal disease screening in Weifang）and 60 normal children who were tested by GESELL from 2002 to 2011 years. Results：No significant different was found in fine movement and individual-social,but distinct different was found in adaptability. big-movement and language between the time of obtaining intinial treatment less than 40 d group and more than 40 d group. No significant different was found in normal children group and cooperative group,but distinct different was found in cooperative group and uncooperative group. Conclusion：Their mental of PKU children by dietary control is normal,the time of early treatment and strictly dietary treatment are very important to those PKU children.
出处
《中国优生与遗传杂志》
2015年第8期121-122,共2页
Chinese Journal of Birth Health & Heredity
