摘要
本文分析了我室自1991年1月至2014年9月的201例唐氏综合征患儿,经外周血染色体G带分析,结果单纯型177例占88.1%,易位型21例占10.4%,嵌合型3例占1.5%.患儿均呈典型的特殊面容和特征,唐氏综合征患病几率高低与人种,生活水准等没有直接联系。因此加强孕前与孕期保健宣传,加强产前诊断,减少唐氏综合征患儿的出生率,对提高优生优育具有十分重要的意义。
Objective：The paper analyzes 201 cases of children with Down syndrome in our hospital outpatient and inpatient from January 1991 to March 2014,Methods：By G-banding chromosome analysis of peripheral blood. Results：The simplex type has 177 cases,accounting for 88.1%,the translocation type has 21 cases,accounting for 10.4%,and the chimeric type has 3 cases,accounting for 1.5%. The children are all in typical features and characteristics,there is no direct link between the risk of Down syndrome and race,living standards of patient. Conclusion：Therefore strengthening care propaganda before conception and during pregnancy;enhancing the prenatal diagnosis and reducing the birth rate of children with Down syndrome,would be of great significance to the promotion of prenatal and postnatal care.
出处
《中国优生与遗传杂志》
2015年第8期57-57,23,共2页
Chinese Journal of Birth Health & Heredity
关键词
唐氏综合征
核型
产前诊断
Down syndrome
Karyotype
Prenatal diagnosis
