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早期复发性流产患者D二聚体及抗凝血酶Ⅲ活性的检测及分析 被引量:7

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摘要 目的探讨早期复发性流产患者血浆D二聚体(D-D)水平及抗凝血酶Ⅲ(AT-Ⅲ)活性的变化。方法选择此次诊断为稽留流产,既往无流产史的患者70例为稽留流产组;此次诊断为稽留流产,既往有≥2次稽留流产史的患者50例为复发性流产组;选择同期在门诊行人流术、既往无流产史的患者62例为正常早孕组。所有入组者均行D二聚体水平及抗凝血酶Ⅲ活性的检测。结果稽留流产组与正常早孕组相比,D二聚体水平及抗凝血酶Ⅲ活性无明显变化,无统计学意义(P>0.05)。复发性流产组与稽留流产组与及正常早孕组相比,D二聚体的水平明显升高,抗凝血酶Ⅲ活性明显降低,有统计学意义(P<0.01)。结论早期复发性流产患者存在血栓形成倾向,D二聚体联合抗凝血酶Ⅲ活性的检测可预测复发性流产发生血栓事件的可能性,改善妊娠结局。
出处 《齐齐哈尔医学院学报》 2015年第21期3136-3137,共2页 Journal of Qiqihar Medical University
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参考文献9

  • 1Baglin T. Venous thrombosis : from bench to bedside and back. In : Hematology Education Book : the education program for the annual congress of the EHA ,2009,3:266-70. 被引量:1
  • 2Dusse LM, Carvalbo MG, Cooper AJ, et al. Tissue factor and tissue factor pathway inhibitor:a potential role in pregnancy and obstetric vascular complications [J ]. Chn Chim Acta,2006,372 (12) :43. 被引量:1
  • 3Gosselin RC, Owings JT, Jaeoby RC, et al. Evaluation of a new automated quantitative D-dimer, Advanced D-dimer, in patients suspected of venous thromboembolism [ J ]. Blood Coagul Fibrinolysis, 2002,13 : 323 -330. 被引量:1
  • 4Eiehinger S. D-dimer testing in pregnancy [ J ]. Semin Vase Med, 2005,5 (4) :375-378. 被引量:1
  • 5Prisco D, Cam G, Faleani M. Hemostatie changes in normal pregnancy [ J ]. Haematol Meet Rep,2005,1 : 1-5. 被引量:1
  • 6Buseri FI, Jeremiah ZA, Kalio FG. Influence of pregnancy and gestation period on some coagulation parameters among Nigerian nntnntnJ woman[ J]. Res ] Marl Sei _2008 _2.275-2R1. 被引量:1
  • 7熊钰,楼懿婷,蔡旭,徐正芳,周容,杨丹,马端,李笑天.正常妊娠分娩前后母胎凝血功能动态变化的研究[J].中国实用妇科与产科杂志,2008,24(5):354-356. 被引量:17
  • 8Sabade J, Casellas M, Alijotas-Reig J, et al. Inherited antithrombin deficiency and pregnancy: maternal and fetal outcomes [J]. Eur J Obstet Gynecol Reprod Biol,2010,149( 1 ) : 47-51. 被引量:1
  • 9Schedin-Weiss S, Richard B, Hjelm R, et al. Antiangiogenic forms of antithrombin specifically bind to the anticoagulant heparin sequence[ J]. Biochemistry,2008,47 : 13610-13619. 被引量:1

二级参考文献9

  • 1Roberts JM, Taylor RN, Musci TJ, et al. Preeclampsia: an endothelial cell disorder[J]. Am J Obstet Gynecol, 1989, 161 (5) : 1200-1204. 被引量:1
  • 2Yin KH, Koh SC, Malcus P, et al. Preeclampsia: haemostatic status and the short-term effects of methyldopa and isradipine therapy [ J ]. J Obstet Gynaecol Res, 1998, 24 ( 3 ) : 231-238. 被引量:1
  • 3Oron G, Ben-Haroush A, Hod M, et al. Serum-soluble CD40 ligand in normal pregnancy and in preeclampsia[ J]. Obstet Gynecol, 2006, 107(4) : 896-900. 被引量:1
  • 4Holmes VA, Wallace JM, Gilmore WS, et al. Tissue factor expression on monocyte subpopulations during normal pregnancy [J]. Thromb Haemost, 2002, 87(6) : 953-958. 被引量:1
  • 5Brenner B. Haemostatic changes in pregnancy [ J ]. Thromb Res, 2004, 114(5-6) : 409-414. 被引量:1
  • 6Tay SP, Cheong SK, Boo NY. Circulating tissue factor, tissue factor pathway inhibitor and D-dimer in umbilical cord blood of normal term neonates and adult plasma[ J]. Blood Coagul Fibrinolysis, 2003, 14(2) : 125-129. 被引量:1
  • 7Heilmann L, Rath W, Pollow K. Fetal hemorheology in normal pregnancy and severe preeclampsia[J]. Clin Hemorheol Microcirc, 2005, 32(3) : 183-190. 被引量:1
  • 8Luther T, Flossel C, Mackman N, et al. Tissue factor expression during human and mouse development[J]. Am J Pathol, 1996, 149(1): 101-113. 被引量:1
  • 9Dusse LM, Carvalho MG, Cooper AJ, et al. Tissue factor and tissue factor pathway inhibitor: a potential role in pregnancy and obstetric vascular complications? [ J ]. Clin Chim Acta, 2006, 372(1-2) : 43-46. 被引量:1

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