摘要
目的:观察盐酸坦洛新缓释片(积大本特)联合托特罗定治疗女性膀胱出口梗阻合并膀胱过度活动症的临床疗效。方法:将87例女性膀胱出口梗阻合并膀胱过度活动症患者随机分成实验组(45例)和对照组(42例),实验组给予盐酸坦洛新缓释片联合托特罗定口服治疗,对照组给予盐酸坦洛新缓释片口服治疗。连续治疗2周,观察2组患者治疗前和治疗2周后的排尿日记(包括排尿次数、夜尿次数、排尿量等)及尿动力学检查指标(包括最大尿流率、残余尿量)。结果:治疗后实验组与对照组各指标较治疗前均有明显改善,但实验组在排尿次数、夜尿次数、最大膀胱容量改善更为显著(P<0.05),且未增加膀胱残余尿量。结论:盐酸坦洛新缓释片联合托特罗定治疗女性膀胱出口梗阻合并膀胱过度活动症的疗效确切,是值得临床推广的治疗方法。
Objective ]To observe the effects of the Tamsulosin and Tolterodine combination treatment of female bladder outlet obstruction .[Method]87 female bladder outlet obstruction patients were devided into experimental （n=45） group and control （n=42 ） group .The experimental group was givenTamsulosin combined with Tolterodinefor two weeks ,and the control group was given only Tamsulosin for two weeks . We observed that theurination frequency , voiding volume , nocturnal frequency , Qmax ,PVRand the parameterswere analyzed by SPSS13 .0 .[Result]Thefrequency ,voiding volume ,nocturnal frequency in experimental group were increased obviously in experimental groupthan that in the control group （ P〈0 .05 ） . There were no obvious difference in Qmax and PVR between the two groups （ P〉0 .05） .[Conclusion]Tamsulosin combined with Tolterodine can be used in the treatment of female bladder outlet obstruction with overactive bladder syndrome showingpositive effects .It is worth spreading .
出处
《浙江医学教育》
2015年第4期55-57,39,共4页
Zhejiang Medical Education
