摘要
目的：探讨人工硬脑膜在重型颅脑损伤大骨瓣减压术中应用效果。方法：分析2010年1月-2014年6月本院收治的100例颅脑损伤大骨瓣减压术行硬脑膜修补患者的临床资料,其中采用人工硬脑膜修补的患者共50例作为观察组,采用自体膜修补的患者共50例作为对照组。所有患者均于术后3~6个月返院行颅骨修补术。观察并对比两组术后皮下积液、脑膨出、颅内感染及癫痫等并发症发生情况及二期颅骨修补术的手术时间、术中出血量、术后引流量及住院费用。结果：两组的术后颅内感染、脑膨出发生率比较差异无统计学意义（P〉0.05）,观察组术后皮下积液和癫痫发生率明显低于对照组,差异均有统计学意义（P〈0.05）。二期颅骨修补手术时,观察组手术时间明显短于,术中出血量明显少于对照组,差异均有统计学意义（P〈0.05）,两组术后引流量比较差异无统计学意义（P〉0.05）。观察组住院费用显著高于对照组,两组比较差异有统计学意义（P〈0.05）。结论：人工硬脑膜安全可靠,能减少术后并发症的发生,并能为二期颅骨修补创造条件,是硬脑膜修补的理想材料,对于经济条件允许的患者首选使用。
Objective： To explore the clinical effect of the biological type artificial dura mater applicated in the big bone flap decompression of craniocerebral injury. Method： The clinical data of 100 patients with craniocerebral injury who received the big bone flap decompression dura repaired were given retrospectively analysis from January 2010 to June 2014, 50 patients were adopted the biological type artificial dura repair as observation group, 50 patients were adopted autologous membrane repair as control group. All patients underwent skull repair 3 to 6 months after the decompression surgery. The postoperative complications such as subcutaneous effusion, encephalocele , intracranial infection and epilepsy, the operation time, intraoperative blood loss , postoperative flow of the secondary phase skull repair surgery and hospitalization expenses were observed and compared. Result： Compared the incidence of postoperative intracranial infection and encephalocele of the two groups, the difference was statistically significant （ P〈0.05 ） ; incidence of postoperative subcutaneous effusion and epilepsy of the observation group were obviously lower than the control group, the differences were statistically significant （P〈O.05） .Second phase skull repair surgery, the surgery time of the observation group was obviously shorter than the control group, intraoperative blood loss was significantly less than the control group, the differences were statistically significant （ P〈0.05 ）, the postoperative flow of the two groups had no statistically significant difference （ P〉0.05 ） . The cost of hospitalization in the observation group was significantly higher than that of the control group, the difference was statistically significant （ P〈0.05 ） .Conclusion： Biological type artificial dura mater is safe and reliable, and can reduce the occurrence of postoperative complications, and create conditions for Ⅱ phase skull repair, it is an ideal material to repair the dura mater.It is the first choi
出处
《中国医学创新》
CAS
2015年第25期66-69,共4页
Medical Innovation of China
关键词
颅脑损伤
大骨瓣减压
硬脑膜修补材料
Craniocerebral injury
Decompression with the large bone flap
Dural repair materials
