摘要
目的探讨大环内酯类抗生素治疗小儿肺炎支原体肺炎的临床效果。方法以本院收治的68例小儿肺炎支原体肺炎患儿为研究对象,根据奇偶原则随机分为对照组与观察组,每组各34例。对照组患儿静脉滴注红霉素,30 mg/(kg·d),观察组患儿静脉滴注阿奇霉素,10 mg/(kg·d),比较分析两组患儿的治疗效果及临床症状改善情况。结果观察组患儿治疗总有效率为91.2%,明显高于对照组(67.2%)(P<0.05)。观察组患儿临床症状改善时间、住院时间、不良反应发生率均低于对照组(P<0.05)。结论阿奇霉素治疗小儿肺炎支原体肺炎的临床效果明显优于红霉素,可有效改善患儿临床症状,缩短住院时间,且不良反应少,安全性高,值得临床推广应用。
ObjectiveTo explore the clinical efifcacy of macrolide antibiotics treating pediatric mycoplasma pneumoniae pneumonia.MethodIn our hospital treated 68 cases children with mycoplasma pneumoniae pneumonia as research objects, according to principle of parity, they were randomly divided into control group and observation group, 34 cases in each group. Children in control group were given 30 mg/（kg？d） erythromycin, intravenous infusion; children in observation group were given 10 mg/（kg？d） azithromycin intravenous infusion, treatment effect and clinical symptoms improved conditions of the two groups were compared.ResultThe total effective treatment rate in the observation group was 91.2%, obviously higher than control group （67.2%） （P〈0.05）. The symptom improvement time, hospitalization time and occurrence rate of adverse reactions in the observation group were lower than control group （P〈0.05）.ConclusionThe clinical effect of azithromycin in the treatment of children with mycoplasma pneumoniae pneumonia is significantly better than that of erythromycin, and it can effectively improve clinical symptoms and shorten the length of hospital stay with less adverse reactions and high safety, worthy of clinical popularization and application.
出处
《中国医学前沿杂志（电子版）》
2015年第6期162-164,共3页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
阿奇霉素
小儿肺炎
支原体肺炎
Azithromycin
Pediatric pneumonia
Mycoplasma pneumonia
