摘要
目的 探讨中西医结合治疗溃疡性结肠炎60例的临床疗效。方法 选取2013年10月~2014年12月我院就诊的溃疡性结肠炎患者120例,所有患者随机分为观察组及对照组各60例。对照组口服柳氮磺胺吡啶片和黄连素片,观察组在此基础上服用中药汤剂。观察两组患者的临床疗效,治疗前后两组症状分级评分及疾病活动指数,毒副作用情况。结果 两组患者总有效率比较,观察组为93.33%,对照组为81.67%,两组比较,差异有统计学意义（P〈0.05）。两组患者治疗后的单项症状积分皆比治疗前明显下降,差异有统计学意义（P〈0.05）。观察组治疗后脓血便、腹痛、里急后重等指标高于对照组,两组比较,差异有统计学意义（P〈0.05）。两组患者治疗后,DAI评分皆比治疗前明显降低,差异有统计学意义（P〈0.05）;观察组治疗后DAI评分明显低于对照组,两组比较差异有统计学意义（P〈0.05）。观察组患者的不良反应发生率为6.67%,明显低于对照组的25.00%,两组比较,差异显著（P〈0.05）。结论 中西医结合治疗溃疡性结肠炎临床疗效显著,明显减少不良反应,值得临床推广应用。
Objective To explore the clinical observation of 60 cases of ulcerative colitis treated with integrated Chinese and Western medicine. Methods 120 patients with ulcerative colitis From October 2014 to December 2013 were randomly divided into observation group and control group with 60 cases in each group. The control group received sulfasatazine tablets and Berberine Tablets, the observation group based on Chinese medicine. Observe the clinical curative effect of two groups of patients before and after treatment, two groups of symptom classification score and disease activity index, toxic side effect were all observed and compared. Results The total effective of the observation group was 93.33%, significantly higher than the control group, which was 81.67%, the difference between the two groups was significant（P 〈 0.05）. The individual symptom scores of the two groups were significantly lower than those before treatment, the difference was significant （P 〈 0.05）. Observation group after treatment, pus and blood stool, abdominal pain and tenesmus index higher than that of the control group, two groups, significant difference（P 〈 0.05）. After treatment, the DAI scores of the two groups were significantly lower than before treatment, the difference was statistically significant（P 〈 0.05）; the DAI score in the observation group was significantly lower than that in the control group, the difference was statistically significant（P 〈 0.05）. The incidence of adverse reactions in observation group was 6.67%, significantly lower than that of the control group（25.00%）, the difference between the two groups was significant（P 〈 0.05）. Conclusion Clinical curative effect of Chinese and Western medicine in treatment of ulcerative colitis is significant, and it is obviously reduced the adverse reactions, it is worthy of clinical popularization and application.
出处
《中国医药科学》
2015年第14期32-34,53,共4页
China Medicine And Pharmacy
关键词
西医治疗
溃疡性结肠炎
中西医结合治疗
疾病活动指数
毒副作用
Western medicine
Ulcerative colitis
Treatment of integrated Chinese and Western medicine
Disease activity index
Toxic and side effects
