摘要
目的了解国内甲真菌病病原菌的种类和构成情况,掌握流行病学资料。方法对真菌镜检阳性的1 428例甲真菌病患者进行真菌培养和临床分析。结果真菌培养阳性率为53.9%,分离出病原菌800株。其中皮肤癣菌占84.0%,以红色毛癣菌为主(80.9%),其次为指(趾)间毛癣菌和絮状表皮癣菌。酵母菌占11.4%,以念珠菌属为主(10.1%),尤以近平滑念珠菌为主,其次为白念珠菌和热带念珠菌。其他霉菌占4.6%,以枝顶孢霉为主(2.3%),其次曲霉属、青霉属、毛壳菌属、镰刀菌属和帚霉属等。结论本研究显示甲真菌病病原菌以皮肤癣菌为主,其次为酵母菌和霉菌。
Objective The aim of this study was to investigate the epidemiology of pathogenic fungi of onychomycosis in China.Methods Fungal culture and clinical analysis were performed on 1 428 cases of onychomycosis using positive direct microscopic examination.Results Eight hundred strains were isolated, the positive rate was 53.9%.The most frequently isolated fungi were dermatophytes （84%）, Trichophyton rubrum accounted for 80.9%, followed by Trichophyton interdigitale and Epidermophyton floccosum. The second was yeasts （11.4%）, Candida accounted for 10.1%, mainly included C.parapsilosis, C.albicans and C.tropicalis.Non-dermatophytic moulds accounted for 4.6%, included Acremonium, Aspergillus, Penicillium, Chaetomium, Fusarium and Scopulariopsis.Conclusion In China, the most frequently pathogenic fungi of onychomycosis were dermatophytes, followed by yeasts and non-dermatophytic moulds.
出处
《中国真菌学杂志》
CSCD
2015年第4期197-202,共6页
Chinese Journal of Mycology
关键词
甲真菌病
病原菌
多中心
流行病学研究
onychomycosis
pathogenic fungi
multicenter
epidemiological survey
