摘要
介绍了DNA同源重组机制确立的过程。其主要内容包括基因连锁和重组现象的发现,交叉假设的提出,断裂重接假设和复制选择假设的出现,同源重组的三个模型(Holliday模型、单链断裂模型和双链断裂模型)的确立。
The establishment of homologous recombination mechanisms is introduced. The key events include tlae alSCover ot gene linkage and recombination phenomena, the proposition of chiasmatype hypothesis, the appear of breakage, reunion and copy choice hypothesis, the establishment of three models of homologous recombination： Holliday model, single-strand-break and double-strand- break repair model for recombination.
出处
《自然杂志》
2015年第4期287-296,共10页
Chinese Journal of Nature
关键词
连锁基因
同源重组
交叉假设
Holliday模型
单链断裂模型
双链断裂模型
linked gene, homologous recombination, chiasmatype hypothesis, Holliday model, single-strand-break model, double-strand-break model
