摘要
目的探讨宫颈电热圈环形切除术（LEEP）不同锥切深度治疗宫颈上皮内瘤变（CIN）对疗效的影响,以期选择最佳的锥切深度,提高治疗水平。方法选取2010年5月~2013年5月130例CIN患者为研究对象,均采用LEEP治疗,将锥切深度分成0.5~1.0 cm,1.0~1.5 cm,1.5~2.0 cm。从切缘阳性率,术后TCT阳性率,早产率等观察治疗后效果差异性。结果 B组切缘阳性率为2.22%、TCT阳性率为4.44%、创面愈合率为97.78%、治愈率为96.63%、复发、CIN残留、二次手术发生率均为4.44%;感染和宫颈管粘连并发症上,B组发生率分别为6.67%、6.67%;妊娠结局上,早产、剖宫产、低体重儿、胎膜早破发生率分别为2.22%、24.44%、2.22%、0.00、0.00,和其他两组比较差异有统计学意义（P〈0.05）。结论 1.0~1.5 cm锥切深度对LEEP治疗CIN疗效最佳,并发症最低。
Objective To investigate electric Hoop cervical excision （loop electrosurgical excision procedure, LEEP） conization different depth treatment of cervical intraepithelial neoplasia （cervical intraepithelial neoplasia, CIN） the im- pact on the efficacy of resistance, in order to select the best cone depth improve the therapeutic level. Methods A total of 130 CIN patients with LEEP treatment were collected from May 2010 to May 2013, the cone cutting depth was disid- ed into 0.5-1.0 cm, 1.0-1.5 cm, 1.5-2.0 cm. positive margin rate, postoperative TCT positive rate, premature birth rate were compared among different depth. Results 1.0-1.5 cm group positive margin rate was 2.22%, TCT positive rate was 4.44%, the rate of wound healing was 97.78%, the cure rate was 96.63%, relapse, CIN residues, reoperation rates were 4.44%; the infection and cervical adhesions complications, 1.0-1.5 cm group rates were 6.67%, 6.67%; on pregnancy outcomes, premature birth, cesarean section, low birth weight children, the incidence of premature rupture of mem- branes was 2.22%, respectively, 24.44 %, 2.22%, 0.00, 0.00, and other differences between the two groups was statisti- cally significant （P〈0.05）. Conclusion 1.0-1.5 cm LEEP cone depth on the efficacy of the treatment of CIN best, lowest comnlication.
出处
《中国现代医生》
2015年第15期27-30,共4页
China Modern Doctor
基金
浙江省医学会临床科研基金项目(2011 ZYC-A64)
浙江省温岭市科技局项目(2009WLCD0060)
