Hcy、hs-CRP、LP(a)和DD联合检测对冠心病诊断的意义被引量：13

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摘要目的探讨同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)、脂蛋白(a)[LP(a)]和D—二聚体(DD)联合检测在冠心病诊断中的意义。方法对136例冠心病患者(急性心肌梗死51例,不稳定性心绞痛48例,稳定性心绞痛37例)和80例正常健康体检者,进行血清Hcy、hs-CRP、LP(a)和血浆DD的浓度检测,并对结果进行统计分析。结果冠心病患者Hcy、hs-CRP、LP(a)和DD浓度显著高于对照组,差异有统计学意义(P<0.01)。冠心病患者各组间比较,急性心肌梗死组上述各指标明显高于不稳定性心绞痛组(P<0.01);不稳定性心绞痛组各指标明显高于稳定性心绞痛组,差异均有统计学意义(P<0.05)。冠心病患者Hcy、hs-CRP、LP(a)和DD的单项阳性率分别为57.35%、67.65%、51.47%、55.88%,四项联合检测阳性率显著高于单项检测(P<0.05)。结论联合检测血清Hcy、hs-CRP、LP(a)和血浆DD,对冠心病预防、早期诊断及动态监测具有重要临床意义。

作者郝建军冯晓鸿袁付平

机构地区高邮市中医医院检验科高邮市人民医院检验科

出处《实验与检验医学》 CAS 2015年第4期469-471,共3页 Experimental and Laboratory Medicine

关键词冠心病同型半胱氨酸超敏C反应蛋白脂蛋白(a) D—二聚体

分类号 R446.112 [医药卫生—诊断学] R541.4 [医药卫生—临床医学]

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