摘要
丹参酮ⅡA是中药丹参的主要成分,具有抗炎、抗氧化、调节细胞凋亡等药理作用,目前广泛用于临床心脑血管疾病的治疗。近年研究发现,丹参酮ⅡA还有具有抗肿瘤、免疫调节、抗多种脏器纤维化等作用。本文在介绍丹参酮ⅡA治疗心血管疾病和神经保护作用的基础上,对近年来国内外丹参酮ⅡA其他方面的药理学作用及疾病治疗方面的进展进行总结。
Tanshinone Ⅱ A, the main ingredient of Chinese medicine salvia miltiorrhiza, has anti-inflammatory, antioxidant, apoptosis regulation and many other pharmacological effects,it is now widely used in clinical treatment of diseases of cardiovascular and cerebrovascular diseases. In recent years, a large number of studies have found that tanshinone Ⅱ A has anti-tumor, anti-fibrosis and immune regulation effects. In this review, we summarize its new progress in pharmacological effects and therapeutic use of tanshinone Ⅱ A on the basis of its function in the treatment of cardiovascular diseases and neural protection.
出处
《实用药物与临床》
CAS
2015年第8期972-977,共6页
Practical Pharmacy and Clinical Remedies
基金
辽宁省科学计划重大疾病动物实验研究及临床应用(2012225021)
辽宁"百千万人才工程"入选项目(2010921072)
关键词
丹参酮ⅡA
心血管保护
神经保护
抗肿瘤
免疫调节
Tanshinone Ⅱ A
Cardiovascular protection
Neural protection
Anti-tumor
Immunoregulation
