摘要
目的 探讨血管内治疗颅内巨大动脉瘤的安全性和有效性。方法 回顾性分析连续收治的74例颅内巨大动脉瘤患者的临床资料,其中采用血管内栓塞治疗57例,保守治疗17例。采用Logistic回归分析检验预后影响因素。结果 17例保守治疗患者随访4-71个月,平均(30.7±7.7)个月,死亡4例,症状加重6例、无变化6例、改善1例。57例血管内治疗患者中,术后即刻造影显示完全栓塞38例,次全栓塞6例,部分栓塞13例;28例影像随访3-63个月,平均(11.7±15.2)个月,复发10例(35.7%);51例临床随访4-71个月,平均(30.7±17.7)个月,42例(73.7%)预后良好(改良Rankin量表评分0-1分)。年龄〉60岁、动脉瘤位于后循环和保守治疗与不良预后显著相关(P〈0.05)。结论 对于年龄〉60岁以及动脉瘤位于后循环的颅内巨大动脉瘤患者,治疗应慎重;血管内治疗颅内巨大动脉瘤复发率较高。
Objective To explore the safety of endovascular treatment of giant intracranial aneurysms(GIAs) and its effects.MethodA retrospective analysis of clinical data of 74 patients with GIAs,of whom 57 were treated by endovascular embolization and 17 were treated conservatively,was made.Of 68 patients who were followed up,17 who were conservatively treated were followed up from 1to 17 months [mean,(31.9±22.6) months] and 51 who were treated by endovascular embolization were followed up from 4 to 71 months[mean,(30.7±17.1) months].ResultsOf 17 patients who were conservatively treated,1 had improved symptoms,6 unchanged symptoms,6 deteriorated symptoms and 4 died.Of 57 patients treated by endovascular embolization,38 received total embolization of GIAs,6subtotal and 13 part.Of these 57 patients,42 were recovered well,4 disabled and 7 died.Of 28 patients who were treated byendovascular embolization followed up by imaging from 3 to 63 months,10(35.7%) had recurrence of GIAs and 18 not.ConclusionThecurative effect of endovascular embolization on GIAs is good,but the rate of recurrence of GIAs treated by endovascular embolization isrelatively higher.
出处
《中国临床神经外科杂志》
2015年第8期469-472,共4页
Chinese Journal of Clinical Neurosurgery