摘要
报告1例进行性结节性组织细胞增生症。患者女,22岁。全身皮肤丘疹和结节6年,皮损进行增多和增大,无自行消退倾向,血脂正常范围,皮损组织病理改变符合梭形细胞性黄色肉芽肿。临床表现结合组织病理改变诊断进行性结节性组织细胞增生症。复习英文文献,至今共有18例报道,该例显著特点是出现黏膜及眼睛受累,免疫组化S-100蛋白阳性在进行性结节性组织细胞增生症中较为少见。
Progressive nodular histiocytosis is a rare variant of non-Langerhans cell histiocytosis （non-LCH）. A 22-year-old female presented with a 6-year history of papules and nodules on the face, trunk, and extremities. Skin lesions increased in number and size, with no sign of spontaneous regression. Serum lipids were within normal ranges. Histopathologic findings were consistent with progressive nodular histiocytosis. The diagnosis of progressive nodular histiocytosis was established accord- ing to its clinical and pathological features. There are a total of 18 cases reported in English literature. Our case distinguish- es itself from others because of the involvement of laryngeal and conjunctival mucosa in combination with polyelonal S-100 positive, which is rare.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2015年第9期555-558,共4页
Journal of Clinical Dermatology
