摘要
目的:观察四磨汤联合肠道微生态制剂对阿尔茨海默病患者认知功能的影响。方法:选取阿尔茨海默病患者28例作为研究对象,将患者随机分为对照组和微生态制剂组,每组14例。对照组给予常规药物加四磨汤口服液治疗,微生态制剂组在对照组治疗的基础上加用金双歧口服治疗。结果:微生态制剂组治疗后MMSE、CDT评分优于对照组(P<0.05);微生态制剂组治疗后瞬间记忆评分显著高于对照组(P<0.05)。结论:四磨汤联合肠道微生态制剂可以改善阿尔茨海默病患者的认知功能,对阿尔茨海默病的治疗具有积极意义。
Objective：To observe the influence of Si Mo Decoction （SMD） in combination with intestinal tract micro-ecosystem preparation on cognitive function of patients with Alzheimer disease （AD）. Methods ：Twenty-eight patients with AD were randomly divided into the control group and the micro-ecosystem preparation group,with 14 cases in each group. The patients in the control group were treated with routine medicine combined with SMD oral fluid ,while the ones in the micro-ecosystem preparation group were added golden bifid for oral administration based on the treatment of the control group. Results ： After the treatment, MMSE and CDT score of the micro-ecosystem preparation group were better than those of the control group（P 〈 0.05 ）. After the treat- ment,the instant score of the micro-ecosystem preparation group was significantly higher than that of the control group （P 〈 0. 05 ）. Conclusion：SMD in combination with intestinal tract micro-ecosystem can improve cognitive function of patients with AD, and have active significance in treating AD.
出处
《河南中医》
2015年第8期1810-1812,共3页
Henan Traditional Chinese Medicine
基金
2013-2014年度山东省中医药科技发展计划项目(编号:2013ZDZK-006)
关键词
阿尔茨海默病
肠道微生态
四磨汤
金双歧
Alzheimer disease （ AD）
intestinal tract micro-ecosystem
Si Mo Decoction （SMD）
gohten bifid
