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安徽省县级医院药品不良反应1944例原因分析 被引量:1

Retrospective analysis of 1 944 adverse drug reaction case reports of county hospitals in Anhui province
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摘要 目的:分析安徽省县级医院药品不良反应(ADR)报告特点及规律,促进临床合理用药。方法:对9家县级医院2012和2013年度上报的ADR报告进行分类和分析。结果:1 944例ADR报告中,给药途径主要为静脉注射(73.8%);累及器官和临床表现主要为皮肤及附件损害(30.3%);药物品种主要为抗菌药物(38.7%);2年度9家县级医院报告ADR的给药途径、累及器官或系统、引起ADR药物品种和不同医院报告病例数构成差异均有统计学意义(P<0.01)。结论:ADR的发生与给药方式、药品种类有关,ADR监测和报告制度在县级医院执行差异较大。 Objective :To analyze the characteristics and regularities of the adverse drug reactions(ADR) in county hospitals of Anhui province, for improving the rational use of drug in clinic, nethocls:A total of 1 944 cases of ADR reports collected from nine county level hospitals of Anhui province from 2012 to 2013 were statistically classified and analyzed. Results: The main cause of ADR was originated from intravenous administration (73.8%);damaging the skin and its appendages was the main lesion in ADR cases (30.3%) ;about 38.7% of ADR cases were mainly caused by using antimicrobial drugs;the difference of the drug delivery route, organs or systems involved,type of drugs and the number of reported cases in different hospital has statistical significance(P 〈 0.01 ). Conclusions: The occurrence of ADR related to the routs of drug delivery and the type of drug, ADR monitoring and reporting system in county hospital execute differently.
出处 《蚌埠医学院学报》 CAS 2015年第7期943-946,共4页 Journal of Bengbu Medical College
基金 安徽省卫生厅医学科学研究项目(13YC002)
关键词 药品不良反应 县级医院 合理用药 adverse drug reaction county level hospital rational use of drugs
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