摘要
目的探讨病理性近视患者b FGF和TGF-β的表达水平。方法对我院门诊就诊的病理性近视患者、非病理性近视患者和正常对照组的b FGF和TGF-β的表达水平进行检测,探讨其在病理性近视患者和非病理性近视患者中的表达强度。结果与正常对照组比较,病理性近视和非病理性近视患者血中b FGF表达明显低于正常对照组,而这两组患者血中TGF-β的表达明显高于正常对照组,差异具有统计学意义(P<0.01)。结论 b FGF和TCF-β可能在病理性近视的发生发展过程序中发挥着一定的作用。
Objective To explore the expression of bFGF and TGF-β and the relationship with pathological myopia. Methods The level of bFGF and TGF-β were detected in patients with pathological myopia and non-pathological myopia and healthy controls. Results The expression level of bFGF were lower in patients with pathological myopia than non-pathological myopia andhealthy controls,and the expression level of TGF-β were higher in patients with pathological myopia than non-pathological myopia and healthy controls,the difference was significant（P 〈 0.01）. Conclusion Conclusion bFGF and TGF-β may play a certain role in the occurrence and development of pathological myopia.
出处
《中国医药科学》
2015年第10期192-194,共3页
China Medicine And Pharmacy
基金
广东省深圳市科技计划项目(201302104)
关键词
碱性成纤维细胞生长因子
转化生长因子Β
病理性近视
Basic fibroblast growth factor（bFGF ）
Transforming growth factor-β （TGF-β ）
Pathological myopia
