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卵泡发育不同阶段黄素化未破裂卵泡综合征卵巢血流动力学变化的研究 被引量:31

Study on Hemodynamic Changes in Ovarian at Different Stages of Follicle Development in Patients with LUFS
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摘要 目的:探讨黄素化未破裂卵泡综合征(LUFS)患者在卵泡发育不同阶段的卵巢动脉血流动力学参数的变化,以预测LUFS的发生。方法:采用经阴道彩色多普勒超声(TV-CDFI)测定34例LUFS患者(LUFS组)54个排卵周期和30例妇女(对照组)50个正常排卵周期的不孕患者,监测两组子宫动脉和两组功能侧卵巢动脉在卵泡发育的3个不同阶段(卵泡早期、卵泡中期和围排卵期)以及两组围排卵期中功能侧和非功能侧卵巢动脉血流动力学的搏动指数(PI)、阻力指数(RI)、最大血流速度(PSV)在组内及组间的变化。结果:1两组子宫动脉的PSV、PI和RI在3个不同阶段的组内和组间比较,差异均无统计学意义(P>0.05)。2LUFS组功能侧卵巢动脉的PSV、PI和RI在3个不同阶段的组内比较,差异均无统计学意义(P>0.05);对照组功能侧卵巢动脉的PSV随着卵泡的增大逐渐增加(P<0.01),RI逐渐降低(P<0.01)。两组功能侧卵巢动脉PSV、PI、RI在卵泡早期和卵泡中期的组间比较,差异均无统计学意义(P>0.05);而在围排卵期中,两组PSV和RI比较,差异有统计学意义(P<0.01)。3LUFS组围排卵期仅功能侧卵巢动脉的PSV值显著高于非功能侧(P<0.01);而对照组围排卵期功能侧卵巢PSV显著高于非功能侧(P<0.01),PI和RI均显著低于非功能侧(P<0.05)。结论:采用TV-CDFI监测卵泡发育不同阶段,围排卵期的卵巢动脉血流动力学变化可以预测LUFS的发生,围排卵期功能侧卵巢血流的灌注不足可能与LUFS的发生有关。 Objective: To investigate the ovarian arterial hemodynamic changes at different stages of follicle development in patients with LUFS for predicting the occurrence of LUFS. Methods: 54 LUFS cycles( 34 cases,LUFS group) and 50 ovulation cycles( 30 cases,control group) underwent serial transvaginal color Doppler ultrasonography( TV-CDFI) examination. The Peak Systolic Velocity( PSV),Pulsatility Index( PI) and Resistent Index( RI) were measured in the two groups of uterine artery and ovarian artery in functional side of follicular development at three different stages( early follicular,mid-dollicular and around ovulation) and functional side ovarian artery around the ovulation period and non-functional. PSV,PI and RI were compared in the groups and between the two groups.Results: 1 In two groups,uterine artery PSV,PI and RI at the three different stages were compared between groups and in groups,the differences were not statistically significant( P〈0. 05). 2The functional side ovarian artery PSV,PI and RI at three different stages were compared in LUFS group,the differences were not statistically significant( P〈0. 05); functional side ovarian artery PSV in control group gradually increased with the follicles development( P〈0. 01),and RI decreased( P〈0. 01). Functional side ovarian artery PSV,PI,RI during the early follicular and mid-follicular phase,the differences were not statistically significant( P〈0. 05); and in the per-ovulation period,the differences of PSV and RI were all statistical significant( P〈0. 01). 3In the per-ovulation period,only functional side ovarian artery PSV in LUFS was significantly higher than that of the non-functional side( P〈0. 01); while in the control group,PSV was significantly higher than the non-functional side( P〈0. 01),PI and RI were significantly lower than the non-functional side( P〈0. 05). Conclusions: Monitoring hemodynamic changes at different stages of follicle development,especially aro
出处 《实用妇产科杂志》 CAS CSCD 北大核心 2015年第8期606-610,共5页 Journal of Practical Obstetrics and Gynecology
关键词 黄素化未破裂卵泡综合征 经阴道彩色多普勒超声 血流动力学 卵巢动脉 Luteinized unruptured follicle syndrome Color Doppler ultrasonography Hemodynamics Ovarian stromal vessals
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参考文献10

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